Oman Daily Observer

Science without gravity at the ISS

- JULIETTE COLLEN

In two decades orbiting the Earth the Internatio­nal Space Station has become a cutting-edge cosmic laboratory, with astronauts researchin­g everything from black holes to disease and even gardening in microgravi­ty.

The ISS, which orbits about 250 miles above Earth, is as large as a football field inside and divided up like a beehive into spaces where the crew can carry out experiment­s with guidance from researcher­s on the ground.

Often, the astronauts are also the experiment­al animals. More than 3,000 scientific tests have been carried out at the ISS since its manned missions began in 2000.

“From a science perspectiv­e, there have been some major discoverie­s,” said Robert Pearlman, space historian and co-author of “Space Stations: The Art, Science, and Reality of Working in Space”. The latest mission — named “Alpha” after Alpha Centauri, the closest star system to our own — will be no exception.

‘MINI-BRAINS’

On Thursday, US astronauts Shane Kimbrough and Megan Mcarthur, the Japan Aerospace Exploratio­n Agency’s Akihiko Hoshide and the European Space Agency’s Thomas Pesquet were to blast off for the ISS aboard the Spacex mission Crew-2.

They are likely to be busy.

Alongside work to maintain the space station itself, around a hundred experiment­s are in the diary for their six-month mission.

These include an acoustic technique using ultrasonic waves to move and manipulate objects or liquids without touching them.

France’s Pesquet has said his favourite planned research is a study examining the effects of weightless­ness on brain organoids — mini brains created using stem cell technology.

Scientists hope this research can eventually help space agencies prepare for distant space missions which will expose crews to the rigours of space for long periods of time, and even help fight brain disease on Earth.

“It really sounds like science fiction to me,” joked Pesquet, an aerospace engineer.

There is ongoing research into what are known as “tissue chips” — small models of human organs that are made up of different types of cells and used to study things like ageing in the immune system, kidney function and muscle loss.

“We don’t fully understand why, but in microgravi­ty, cell-to-cell communicat­ion works differentl­y than it does in a cell culture flask on Earth,” said Liz Warren, senior programme director at the ISS US National Laboratory, adding cells also gather together differentl­y.

“These features allow cells to behave more like they do when inside the body. Thus, microgravi­ty appears to provide a unique opportunit­y for tissue engineerin­g.”

Another important element of the mission is upgrading the station’s solar power system by installing new compact panels that roll open like a huge yoga mat.

Crew-2’s launch day coincides with Earth Day, and by the time the crew returns they will have also contribute­d to environmen­tal research by taking 1.5 million images of phenomena like artificial lighting at night, algal blooms, and the breakup of Antarctic ice shelves.

From a science perspectiv­e, there have been some major discoverie­s since its manned missions began in 2000

ROBERT PEARLMAN Space historian

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