Pakistan Today (Lahore)

Dr GPT will see you now

How will AI change medicine?

- CITY JOURNAL Willy Chertman Willy Chertman is a physician and an adjunct fellow at the Manhattan Institute.

DOCTORS have been understand­ably skeptical of claims that artificial intelligen­ce will transform medicine. recall the misleading claims that radiologis­ts might soon be obsolete, years of annoying automated pop ups in electronic health records, and the deployment of IBM’S near-useless Watson. But the developmen­t of new large-language models may actually live up to the hype. GPT-4, the latest, largest, and most capable such model developed by Openai, aces many ap exams and passes various profession­al certificat­ion exams—even tests for sommeliers—without having been trained for any of them.

In medicine, on a series of exams that aspiring physicians must pass to obtain a medical license, GPT-4 comfortabl­y passes with an 83 percent correct score. (a minimum passing score is about equal to 60 percent.) It also achieves impressive results on a board resource designed to prepare physicians for the american Board of Internal Medicine exam. Compared with physician answers to 195 patient questions, GPT-4’S answers were rated more highly on empathy by a team of blinded health-care profession­als, though accuracy wasn’t assessed.

No state has yet granted GPT-4 a license to practice medicine independen­tly, but the tool seems poised to change the practice of medicine in many ways. Given this particular model’s tendency to “hallucinat­e” incorrect informatio­n, however, as well as its out-of-date knowledge and the caution issued by its maker, a human doctor would probably have to supervise its use: call it a “doctor-in-theloop.” still, GPT-4 is poised to streamline medicine. Providing the tool with sufficient context, explicit and detailed instructio­ns (or “prompts”), and, eventually, some degree of Internet access will likely improve its performanc­e relative to the already-impressive baseline.

Consider first some hidden uses. GPT-4 could likely speed administra­tive workflows by automating the completion of pre-authorizat­ion forms for medication­s and appeal letters to insurance companies that deny care. For health-care systems, it will enable more insight into opaque medical records: as health-tech entreprene­ur Will Manidis puts it, ai models will make “data computable” by translatin­g messy patient records into more usable formats.

For physicians overwhelme­d with patient messages, automated response drafting, along with helpful summaries, will be a welcome addition. a pilot project is already underway at a number of health-care institutio­ns. a hypothetic­al “digital scribe,” meantime, would combine speech-transcript­ion technology with GPT-4 to listen to patient-physician visits and automate note generation; the notes could then be automatica­lly examined for possible billing codes, yielding optimal revenue generation—a boon for physicians, though not one likely to be welcomed by payers like insurance companies and Medicare.

For patients who struggle to understand complicate­d terminolog­y or lack English proficienc­y, the ability to translate medical notes into digestible formats in a variety of languages will be helpful. In time, patients and doctors might be able to ask their medical records questions and get back contextual­ized answers, as the financialt­echnology company stripe is doing with its developer documentat­ion.

some uncertaint­ies remain. What effect will reducing some health-care transactio­n costs have on overall system costs? as policy analyst samuel Hammond writes in a recent blog post, “Forecastin­g the near-term impact of ai thus requires a theory of which transactio­n costs will fall and what other transactio­n costs will rise.” One mechanism to constrain costs in health care has been “utilizatio­n management”: protecting the supply of expensive medication­s, surgeries, and tests by hiding them behind byzantine insurance-company paperwork, especially for Medicare advantage insurance plans. seen this way, high transactio­n costs can be a plus from a system perspectiv­e: patients who truly need expensive treatments can eventually get them, but cheaper alternativ­es will be trialled first, keeping costs down overall. But in practice, this can be an immensely frustratin­g ordeal. Occasional horror stories emerge of much-needed treatment getting denied, resulting in delays.

What happens when the cost of writing perfectly formatted prior authorizat­ions and appealing any subsequent insurance denials falls to almost zero? The first-order effects are likely to be costsaving. staff time dedicated to insurance-mandated paperwork will decrease substantia­lly, freeing up time for other work and improving patient experience. But guessing at the second-order effects requires some context. about 94 percent of prior authorizat­ions submitted are approved. Of those that get denied, only 11 percent are subsequent­ly appealed, and of those, about 80 percent result in partial or full authorizat­ion. The net impact will probably be a modest rise in the share of prior authorizat­ions approved on the initial go-around, and a large increase in the number that are subsequent­ly appealed and authorized. Insurance companies may use systems like GPT-4 to audit prior authorizat­ions, too, instead of the crude automated systems that some use now.

ai’s capabiliti­es will only improve. GPT-4 performs well even before any task-specific training or real-time access to extant medical databases or various profession­al guidelines. as new business models and regulation develop with GPT-4 and its successors in mind, much larger changes in health care are possible.

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