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Covid boosts risks for mental, neurologic­al disorders in study

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Athird of Covid-19 survivors were diagnosed with a neurologic­al or psychiatri­c condition in the six months after being infected, according to the first large-scale research to compare the risks to other illnesses, including influenza.

the University of Oxford study analyzed health records of 236,379 Covid-19 patients infected last year, according to a report in journal. As might be expected, anxiety and mood disorders were the most common diagnoses, at 17 percent and 14 percent of patients respective­ly. But the study also found 7 percent of those made sickest by the virus had a stroke and 2 percent were diagnosed with dementia.

While the investigat­ors stressed that the specific causes of these long-term effects are largely unknown, they suggested some of them might be linked to stress, job loss or loneliness during quarantine. More in-depth research is needed on the neurologic­al risks and more resources are needed to address the full range of implicatio­ns, they said.

“Although the individual risks for most disorders are small, the effect across the whole population may be substantia­l for health and social-care systems due to the scale of the pandemic and that many of these conditions are chronic,” said Paul harrison, a professor of psychiatry at the university and the study’s lead author.

the researcher­s also explored data from 105,579 people with influenza and 236,038 patients with any respirator­y tract infection. there was a 44 percent greater risk of neurologic­al and mental-health diagnoses after Covid-19 than after flu, and a 16 percent greater risk than with respirator­y tract infections.

“Although we know that the virus can access the brain, it’s not necessaril­y only the neurons in the brain that might be effected,” said Masud husain, professor of neurology and cognitive neuroscien­ce at the University of Oxford. “We need to be careful about what we attribute the effect of the virus to the brain itself.”

Brain fog

At the start of the pandemic, a number of Covid patients whose symptoms were initially mild developed long-term neurologic­al problems, what survivors refer to as“brain fog.”at the time there was no strong evidence that Covid-19 infects the brain. however, since then there have been several other studies that have made the link between Covid-19 and increased risk of neurologic­al disorders.

A study published last October found that about 4 of 5 patients hospitaliz­ed with Covid-19 suffer neurologic­al symptoms, including muscle pain, headaches, confusion, dizziness and the loss of smell or taste. Another study from Wuhan, China, where the virus first appeared, found that 36 percent of patients had neurologic­al symptoms ranging from headache to impaired consciousn­ess.

A limitation of the Oxford study is that the researcher­s only analyzed records of patients diagnosed with Covid, which does not take into considerat­ion people who were infected but had no symptoms.

Some of patients in the control cohort“might have also had Covid,” said Max taquet, a study coauthor. “We didn’t know that.” it means the findings could have underestim­ated the relative risk of developing neurologic­al or mental-health disorders.

Still, the overall message is clear, according to taquet.“we need to be proactive and establish followup strategy for patients who have had Covid,”he said, adding that health-care providers should be prepared to address an increased demand for assessment and treatment of these disorders. Bloomberg News

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