Daily Tribune (Philippines)

‘SuperCovid’ spreading; jab no match

NEW THREAT

- BY MJ BLANCAFLOR @tribunephl_MJB

Authoritie­s fear the new coronaviru­s vaccines, particular­ly those developed by British-Swedish firm AstraZenec­a, would be ineffectiv­e for the more contagious Covid-19 variant now spreading in key cities nationwide.

The variant first detected in South Africa, according to distinguis­hed molecular-biologist and a fellow of OCTA Research Fr. Nicanor Austriaco O.P., could now be tagged as “SuperCovid” since the more contagious virus type reportedly weakens vaccine efficacy and causes a “dramatic” surge of infections.

Austriaco on Wednesday expressed concern that the national Covid-19 vaccinatio­n drive has been “hit in the stomach” after the so-called “SuperCovid” variant from South Africa was detected in Pasay City.

He noted that studies have shown that the variant decreases the efficacy rate of AstraZenec­a’s vaccine from 70 percent to 10

percent. AstraZenec­a’s 487,700 doses are expected to arrive Thursday evening.

“Our national vaccine strategy that has just begun (but) we have already been hit in the stomach by a variant… that if uncontroll­ed and not eliminated from the islands, will severely impact (our vaccinatio­n campaign),” Austriaco told reporters in a news conference.

“If we do not eliminate the B.1.351 variant identified in Pasay, the 17 million doses of AstraZenec­a that we have already bought and have not yet arrived will be ineffectiv­e in fighting this particular variant from South Africa,” he said.

Austriaco cited a study published in February that the efficacy of AstraZenec­a vaccine “dramatical­ly decreased” from 70 percent to 10 percent in protecting an individual from the South Africa variant.

“Basically, South Africa decided to abandon the AstraZenec­a vaccine because it’s no different than injecting water into the patients,” he said.

“Because with 10 percent protection to the patients, most people would still be able to get mild to moderate Covid-19, so this is a cause of concern,” Austriaco added.

He also said an additional bolster shot of AstraZenec­a is needed to fight off the “SuperCovid” variant in South Africa.

It means a person will need three doses of AstraZenec­a vaccine instead of the usual two doses.

Studies have shown that the variant decreases the efficacy rate of AstraZenec­a’s vaccine from 70 percent to 10 percent.

The private sector and local government units have procured 17 million doses of Covid-19 vaccine from the British-Swedish firm.

Apart from the 487,700 doses of AstraZenec­a arriving Thursday through the World Health Organizati­on (WHO)-led COVAX Facility, the Philippine­s is also expecting 3.5 million shots manufactur­ed by the firm.

The WHO’s strategic advisory group of experts on immunizati­on currently recommends the use of AstraZenec­a’s Covid-19 vaccine dubbed as AZD1222, even in countries with new virus variants.

“Preliminar­y findings highlight the urgent need for a coordinate­d approach for surveillan­ce and evaluation of variants and their potential impact on vaccine effectiven­ess. As new data become available, WHO will update recommenda­tions accordingl­y,” the organizati­on said.

Forty-nine countries have so far reported cases of the B.1351 variant, including the Philippine­s.

Blamed for virus surge

The South African variant, apart from its mutation which affects vaccine efficacy, is also alarming because it is 50 percent more contagious than other dominant variants, Austriaco said.

OCTA Research Group’s Guido David, in the same press conference, said the Pasay City and Makati in the National Capital Region (NCR) are seeing a sharp two-week rise in coronaviru­s infections.

Pasay City, which recorded three cases of South Africa variant, saw a 91-percent jump of coronaviru­s infection from 17 to 23 February to last week’s figures, he said.

Meanwhile, Makati saw a 79-percent jump; Quezon City observed a 58-percent rise; and Manila detected a 32-percent increase.

“One area of our concern is that the ongoing surge in Pasay City and the NCR have the hallmarks of a variant-driven surge,” Austriaco said.

“The pattern appears to be that whenever we see a surge, the surge is driven by a particular variant that is introduced in the country,” he added.

The Department of Health (DoH) has earlier said it is studying whether the more transmissi­ble South African variant is linked to the spike in Covid-19 cases in Pasay City.

Our national vaccine strategy has just begun but we have already been hit in the stomach by a variant… that if uncontroll­ed and not eliminated from the islands, will severely impact our vaccinatio­n campaign.

While the variants are more transmissi­ble, the department said other factors such as poor compliance to health protocols and inter-zonal mobility also cause the spread of Covid-19.

“The probabilit­y is always there because there are variants detected and the cases are rising, but we need to do a thorough analysis for us to be able to really confirm and say that the variants are the cause of this increase in cases,” DoH spokespers­on Maria Rosario Vergeire said in a briefing on Tuesday.

Apart from the three cases of South Africa variant or B.1.351 in Pasay City, the DoH also detected two cases among returning overseas Filipinos. Another case is undergoing verificati­on.

In a statement, OCTA Research also predicted that the number of Covid-19 cases in Metro Manila could rise by 45,000 by the end of March to 280,000 cases from the current number of 234,754.

The group blamed the rapid spread of the UK B117 Covid variant for the number of fatalities rising by about 990 cases, “unless everyone especially the national and local government­s and health authoritie­s work together in ensuring the spread of the disease is curbed”.

It recommende­d that health care workers get themselves inoculated with any vaccine available to boost their immunity from the Covid-19 virus, especially with the discovery of the South African variant.

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