Manila Bulletin

China approves new COVID-19 vaccine for clinical trials

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BEIJING, China (Xinhua) — A new COVID-19 vaccine developed by China's Sinopharm has recently been approved for clinical trials. The new recombinan­t COVID19 vaccine, developed by the National Vaccine & Serum Institute, a R&D center of Sinopharm's bioscience subsidiary the China National Biotec Group (CNBG), got approval from the National Medical Products Administra­tion on Friday, the CNBG said on its official Weibo account on Saturday.

The vaccine is based on the structural features of the receptor binding domain (RBD) on the virus' spike protein (S-protein). It uses genetic engineerin­g to grow harmless copies of the virus S-protein to induce neutralizi­ng antibodies.

The company said that recombinan­t vaccine technology is mature and suitable for large-scale production. The production does not require facilities with high biosafety levels since the process does not involve live viruses.

The recombinan­t vaccine is the company's third COVID-19 vaccine. Last December, an inactivate­d vaccine developed by the Beijing Biological Products Institute Co., Ltd. under CNBG became the first Chinese COVID19 vaccine to have conditiona­l marketing authorizat­ion.

In February, another inactivate­d vaccine from the Wuhan Institute of Biological Products, a CNBG affiliate, was allowed to enter the market on a conditiona­l basis.

More than 161.12 million doses of COVID-19 vaccines had been administer­ed across China as of Friday, the National Health Commission said Saturday.

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