Philippine Daily Inquirer

DIETARY FATS ARE PROTECTIVE, CARBOHYDRA­TES ARE HARMFUL

- By Augusto D. Litonjua, MD FPCP, FPSEDM, FACE President, Diabetes Center Philippine­s

Cardiovasc­ular disease (CVD) is a global epidemic with 80% of the people affected as belonging to the low-income and middle-income countries. Diet is one of the most important factors which can increase the risk for CVD, and at the same time, the most modifiable of the risk factors that can prevent CVD.

Current guidelines recommend a low fat diet – meaning less than 10% of the total daily energy intake. Also, these guidelines suggest replacing the “very bad fats”, called saturated fats (see table) with the “good fats”, - the monounsatu­rated and polyunsatu­rated fats.

In recent years however, the foregoing thinkings have been proven to be quite untrue, with the real culprit for CVD, and the Metabolic Syndrome, which increases the risk for CVD, are SUGARS and not FATS.

Metabolic Syndrome is a cluster of clinical states (type 2 diabetes mellitus, hypertensi­on, high triglyceri­des and low HDL or good cholestero­l which are driven by a fatty liver state, which in turn, is due to an abnormal response of the liver to insulin (insulin resistance). Metabolic syndrome (note that the cluster of clinical states does not include total cholestero­l or the bad cholestero­l, LDL) increases the

risk for CVD, all people (especially those with big bellies) to be susceptibl­e for the Metabolic Syndrome. This Syndrome which is increasing worldwide in almost epidemic proportion­s, is due to unhealthy dietary habits – especially with the increased intake of alcohol, trans fats (the only bad fat, actually – see Table) and most especially to a sugar – FRUCTOSE.

A recent study called PURE (Prospectiv­e Urban and Rural Epidemiolo­gy) published online 29 August 2017 and reported at the recent European Society of Cardiology Congress which included both Asian and Western countries ( 18 countries in 5 continents) and involving 135,335 subjects showed that dietary fats are protective to CVD, while carbohydra­tes are harmful. The dietary habits of these subjects were categorize­d into nutrient intakes of carbohydra­tes, fats and proteins. These were then related – after a follow-up of 5 – 9 years – to the number of deaths in the subjects. There were 5796 deaths recorded and the highest carbohydra­te intake was associated with an increased risk of total mortality. Intake of total fat and each type of fat was associated with the lower risk of total mortality. Higher saturated fat intake was associated with lower risk of stroke.

Total fat, saturated fat, and polyunsatu­rated fat were not significan­tly associated with risk of heart attack (myocardial infarction) or CVD mortality.

Their conclusion­s are summarized as follows:

1. Decreasing overall mortality with increasing consumptio­n of saturated fat, but no effect on CVD mortality. 2. Increasing mortality with increasing consumptio­n of carbohydra­tes. 3. Current guidelines recommendi­ng less than 10% saturated fat not supported by data. 4. Results challenge current guideline recommenda­tions on intake of saturated fat and carbohydra­tes.

In an earlier study published in 2013, called An Internatio­nal Longitudin­al Panel Analysis of Diet and Diabetes pointed specifical­ly to sugars as the responsibl­e component of carbohydra­tes as the real culprit. 1. Only changes in sugar availabili­ty correlated with changes in diabetes prevalence (and the Metabolic Syndrome, and hence CVD), 2. Every extra 150 calories increased diabetes prevalence by 0.1%. 3. But, if those 150 calories were a can of soda, diabetes prevalence increased to 1.1%. 4. These data estimate that 25% of diabetes worldwide is explained by sugar. And that sugar is FRUCTOSE, or fruit sugar.

The panel said: The sources of fructose are:

1.

Fruits. Fruit juice is not good, but fresh fruits in moderation are good. The difference between the two, is that fresh fruits contain roughage which prevents the rapid absorption of fructose into the body, and provides food for the good bacteria in our gut. 2. Honey and table sugar 3. High fructose corn syrup – the worst offender, which is the sweetener for a variety of sugar sweetened drinks – soft drinks and “power” drinks.

And so, as said in the article of Maryanne Demasi (investigat­ive reporter), Robert Lustig (pediatric endocrinol­ogist) and Aseem Malhotra (cardiologi­st) in their publicatio­n in Clinical Pharmacist of 4 July 2017, the cholestero­l and calorie hypotheses are both DEAD!

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LITONJUA

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