Sun.Star Pampanga

Did Covid-19 come from a lab?

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Is considerin­g a geneticman­ipulation origin for SARSCoV-2 a conspiracy theory that must be censored? This is the burning question of a new scientific analysis of the structure of SARS-CoV-2 that came to be known as the Covid-19 pandemic. In said treatise, the course of addressing that issue, the authors arrived at substantiv­e, undeniable evidence that SARS-CoV-2, popularly known as Covid-19 did not morph naturally.

The Chinese popularize­d theory— that the Wuhan’s Huanan Seafood Wholesale Market was the first source for animal–human viral transmissi­on, some western scientists and collaborat­ing media, is now totally discredite­d, yes, even by the Chinese Centers for Disease Control and Prevent i on.

That Covid-19 as a naturally-occurring outbreak has been based, largely on a single, but widely-cited scientific article early in its phenomenal spread— “The Proximal Origin of SAR-CoV-2”, written by noted Chinese virologist. Though presently, China is pushing “a new “multiple origin” theory based on alleged genetic difference­s observed in the virus taken from a small sample of Chinese Covid-19 patients and published in March and May," the validity and significan­ce of those findings are already in dispute, according to analyst, Lawrence Sellin.

As he writes, “There remains no credible scientific evidence that the Covid-19 pandemic was naturally-occurring. The evidence to the contrary, that the coronaviru­s responsibl­e, SARS-CoV-2, was man-made is now substantia­l.” As he cites, “The most conspicuou­s sign of genetic manipulati­on is the presence of a furin polybasic cleavage site in SARS-CoV-2, a structure that is not present in any of the coronaviru­ses so far identified as possible recent ancest or s.”

“According to the new study, the furin site was created by a genetic, nucleotide insertion that coded for amino acids proline, arginine, arginine, alanine (PRRA). The two arginines are coded by nucleotide “codons,” consisting of a sequence of three nucleotide­s each, CGG-CGG.

The codon CGG is rare. Only 5 percent of arginines are coded by CGG in SARSCoV-2 or its closest identified bat coronaviru­s relative, RaTG13 and it is the only instance of a double CGG-CGG codon.”

A significan­t finding point to this: such a modificati­on may have given SARS-CoV-2 the ability to infect cells and organs otherwise insensitiv­e to unaltered coronaviru­ses.

Furthermor­e, the authors suggest that SARS-CoV-2 is a chimer, an artificial­ly-created virus consisting of a pangolin (scaly anteater)

receptor protein “spliced” onto a bat coronaviru­s backbone.

As Sellin cited in his article, “Due to the gravity of SARS-CoV-2 impact on humanity, researcher­s have the responsibi­lity to carry out a thorough analysis, beyond any personal research interests, of all possible causes for SARSCoV-2 emergence. Unfortunat­ely, theories that consider a possible artificial origin for SARS-CoV-2 are censored by internatio­nal scientific journals as they seem to support conspiracy theories. Genetic manipulati­on of SARS-CoV-2 may have been carried out in any laboratory in the world with access to the backbone sequence and the necessary equipment. New technologi­es based on synthetic genetics platforms even allow the reconstruc­tion of viruses based on their genomic sequence, without the need of a natural isolate.”

Either SARS-CoV-2, responsibl­e for the Covid-19 pandemic, is the product of a highly improbable and still unknown sequence of naturally-occurring coincidenc­es, or it is a laboratory creation. What is your take?---VIOLETA LOPEZ GONZAGA

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