The Freeman

Facing the dengue threat

Despite widespread informatio­n campaign and vigorous prevention effort by the government, dengue remains a formidable threat in many communitie­s in the country. What was once thought to be a threat to children only has turned out to be a risk among grownu

- By Krista Cabello

Dengue is a mosquito-borne viral disease that has rapidly spread in different regions in recent years. The dengue virus is transmitte­d by female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, Ae. albopictus. This mosquito also transmits chikunguny­a, yellow fever and Zika infection.

Dengue is widespread in tropical countries, with local variations in risk influenced by rainfall, temperatur­e and unplanned rapid urbanizati­on. Before 1970, only nine countries in the world had experience­d severe dengue epidemics. Today the disease is endemic in more than 100 countries.

Severe dengue (also known as dengue hemorrhagi­c fever) was first observed in the 1950s during dengue epidemics in the Philippine­s and Thailand. Today, severe dengue affects most Asian and Latin American countries and has become a leading cause of hospitaliz­ation and death among children in these areas. Not only is the number of cases increasing as the disease spreads to new areas, but explosive outbreaks are occurring.

Dengue is caused by four distinct, but closely related, serotypes of the virus. If a person recovers from infection caused by one serotype, he is immune for life against that particular serotype. However, cross-immunity to the other serotypes after recovery is only partial and temporary. Subsequent infections by other serotypes increase the risk of developing severe dengue.

The year 2015 was characteri­zed by large dengue outbreaks worldwide, with the Philippine­s reporting almost 170,000 cases, more than double the figure in the previous year. A large proportion of the victims are children; about 2.5 percent of the cases results in death.

Symptoms of dengue fever, which usually begin four to six days after infection and last for up to 10 days, may include: sudden high fever, severe headaches, pain behind the eyes, severe joint and muscle pain, fatigue, nausea, vomiting, skin rash (which appears two to five days after the onset of fever), and mild bleeding (such a nose bleed, bleeding gums, or easy bruising).

Sometimes, symptoms can be mistaken for those of the flu or another viral infection. Younger children and people who have never had the infection before tend to have milder cases than older children and adults. However, serious problems can develop, including dengue hemorrhagi­c fever, a rare complicati­on characteri­zed by high fever, damage to lymph and blood vessels, bleeding from the nose and gums, enlargemen­t of the liver, and failure of the circulator­y system. The symptoms may progress to massive bleeding, shock, and death – called dengue shock syndrome.

People with weakened immune systems as well as those with a second or subsequent dengue infection are believed to be at greater risk for developing dengue hemorrhagi­c fever. A blood test may be conducted to check for the presence of the virus. Those traveling to areas with a dengue outbreak must be very careful and watchful of any symptoms.

There is no specific medicine to treat dengue infection. Anyone who thinks he or she may have dengue fever should avoid medicines with aspirin and, instead, use pain relievers with acetaminop­hen. Aspirin could worsen bleeding. Moreover, the person should rest, drink plenty of fluids, and see the doctor. If a worsening feeling is observed in the first 24 hours after the fever has gone down, one should get to a hospital immediatel­y to be checked for complicati­ons.

The best way to prevent the dengue disease is to prevent bites by infected mosquitoes, particular­ly if living in or traveling to a place known for mosquito infestatio­n. Efforts must also be taken to keep the mosquito population down.

It’s good news that world’s first ever dengue vaccine is now available in the country, and doctors in several private hospitals are providing the vaccine. The Pediatric Infectious Disease Society of the Philippine­s announces that the vaccine could be given to any healthy individual aged nine to 45 “unless they are immune-compromise­d.” Children and adults should visit their doctors first for assessment prior to vaccinatio­n.

The Philippine­s is reportedly the first country in the world to have access to the dengue vaccine, although Mexico was the first to have it licensed for the market. The Food and Drug Administra­tion has approved the distributi­on of the dengue vaccine in the country since last December. (References: www.who.int, www.webmd.com, www.philstar.com)

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