The Philippine Star

A nasal spray against COVID-19

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The nasal surface is the first entryway for the environmen­tal pollutants, infections and viruses. with COVID-19, a multifacto­rial disease caused by coronaviru­s, nearly 90 percent of COVID-19 infections are through the nasal cavity.

The COVID-19 virus surface contains many protruding spikes known as glycoprote­ins that binds to the ACE-2 receptors situated on the nasal mucosa cells.

This allows the virus to enter and attack new healthy cells that likewise open entryways for infection passage into the body circulatio­n.

The onset of COVID symptoms reveals that the virus is already disseminat­ed in the body. The primary symptoms of the disease include cough, fever, loss of taste and smell, body pain, sore throat, eventually followed by the severe respirator­y distress.

To prevent all these from happening, action must be taken at the entry gateway (nasal mucosa) of the virus.

Nasal wash with water or salt solutions might help reduce the virus particles in the nasal mucosa. However, this is ineffectiv­e as the virus continues to grow and produce new particles in the nasal mucosa cells. In addition, such treatment must be used very frequently.

Covispray is a glycerol-based, osmotic, filmogen solution, containing two jellifying agents and a few specific dual-acting polymers.

Thumkesh Khera, chairman of Preventia Healthcare Inc., shared: “When Covispray is sprayed on the nasal mucosa, it forms a stable osmotic film instantly. Osmosis creates a strong hypotonic liquid flow from the nasal tissue that swells the jellifying agents and renders the film absorbent. The osmotic liquid flow also cleans the nasal surface by detaching and draining the contaminan­ts present on the nasal mucosa. The film creates a physical barrier on the nasal surface to prevent incoming virus particles with the nasal mucosa. A clean nasal mucosa reduces the inflammati­on and offers good environmen­t for cells to grow and reconstitu­te a natural, intact nasal defensive barrier.”

The purpose of Covispray is not to replace any recommenda­tion directed by the physicians.

“However, it is a complement­ary measure which is helpful to avoid disease progressio­n. Its efficacy in preventing the spread of disease is clinically proven. The severity of the infection has been reduced within two days of Covispray usage,” adds Thumkesh.

Covispray is a safe and instant topical treatment to supress and stabilize the disease progressio­n. It can also be used regularly as a precaution­ary measure to prevent the upload of virus in your day-to-day routine.

Covispray will be available at Mercury Drug this September.

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