This is the most advanced organ-on-a-chip, designed by Harvard’s Wyss Institute. The chip acts just like a human lung and has already helped scientists test new drugs and look for markers for asthma and chronic obstructive pulmonary disease. The chip can be seeded with diseased cells from a patient, which retain their ailments when planted in the chip. This allows researchers to find better treatments for a specific patient’s needs.
In the diagram below, you can see how Wyss Institute researchers triggered a response to infection in the chip.
The lung-on-a-chip is about the size of a memory stick. It is made of clear, rubber material and contains hollow channels Rhythmic suction is applied so the cells contract and relax, to mimic breathing motions 2. As bacteria start to attack the lung...