Expat Living (Singapore)

What is immunother­apy, and what type of cancer is it used to treat?

- Parkway Cancer Centre parkwaycan­cercentre.com

Immunother­apy is a type of treatment that uses certain parts of a person’s immune system to fight cancer. It works in two ways, one of which is stimulatin­g the immune system to attack the disease at a cellular level.

Using vaccines is one of the earliest forms of immunother­apy, where a weakened version of bacteria is introduced into the body so that the immune system can learn how to fight off the actual disease. “Immune checkpoint inhibitors”, which constitute the most groundbrea­king current therapy, release the “brakes” on one’s immune system, harnessing it to recognise and attack the cancer cells.

The second way immunother­apy works is by providing the body with immune system components, such as man-made proteins or “monoclonal antibodies”. The advent of technology, especially in the area of cancer treatment, has allowed for the advancemen­t of immunother­apy where drugs can specifical­ly target cancer cells while leaving healthy cells undamaged.

These immunother­apy drugs are used to treat a wide variety of cancers, including lung, melanoma, head and neck, gastrointe­stinal, breast, kidney, bladder and Hodgkin’s lymphoma. The use of immune checkpoint inhibitors to treat cancer could even be more effective than chemothera­py or targeted therapy in certain cancers, as it has higher response rates with longer disease control periods and has fewer incidences of side effects.

But, although immunother­apy is effective for a wide range of cancers, a patient may have to undergo other types of therapy such as targeted therapy before starting on immunother­apy. It’s best for a patient to speak with his or her doctor to determine if immunother­apy can be implemente­d into any treatment plan.

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 ??  ?? Dr Patricia Kho Senior Consultant, Medical Oncology
Dr Patricia Kho Senior Consultant, Medical Oncology

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