Scientists research anti-smoking vaccine

LONDON: An injection of genes that make antibodies against nicotine may help smokers kick the habit.

Just one jab can provide life-long protection against nicotine cravings and it can eventually be used to vaccinate children to stop them from ever getting hooked.

The “genetic vaccine” has only been tested on mice, but research on people may begin in about two years.

The jab contains genes “programmed” to make antibodies that neutralise nicotine before it reaches the brain, where it would normally trigger the pleasurable feelings that underlie addiction.

The theory is that if smokers no longer get such gratification from cigarettes, they will find it easier to quit. The jab being developed at Weill Cornell Medical College in New York tricks the liver into continuously making antibodies, ensuring there are always some in the blood to fight nicotine.

Darren Griffin, professor of genetics at Kent University, said the study had “great potential”, but warned that it might not work in humans.

Professor Anthony Dayan, a retired toxicologist, said: “Nicotine addiction via smoking is harmful, but is it ethical to produce a major and enduring change in someone’s body to prevent it when other, less major, types of treatment are feasible?” – Daily Mail