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World Immunisati­on Week is marked every year in the last week of April. It aims to promote the use of vaccines to protect people of all ages against disease

- NOKUTHULA MABUZA nokuthula.mabuza@inl.co.za PROFESSOR TERRENCE KOMMAL Kommal is a medical doctor and chairman of the Medical Expert Consulting Group. He is also a Young Global Leader of the World Economic Forum.

OLD age homes in KwaZulu-Natal say their residents are looking forward to being vaccinated against the Covid-19 virus.

The vaccinatio­n rollout for phase 2 – for those over the age of 60 – is expected to start in May.

Dave Naidoo, the chairperso­n of the Aryan Benevolent Home in Pietermari­tzburg, which will celebrate its 100th anniversar­y on May 1, said they spoke to their residents about the vaccinatio­n rollout.

“They are open to the suggestion of taking the vaccinatio­n.

“I think the fact that we suffered the tragic loss of 13 residents to Covid-19 last year, made them realise that they need to be protected and avoid being

IN RECENT times, nothing has impacted the livelihood­s of families globally like the Covid-19 pandemic.

There has been great efforts and recommenda­tions of what people could and could not do to reduce the transmissi­on of the virus. Prevention was our initial target, then there was a protection focus that included masks and sanitation, and good practices.

Then there were treatments on what should be done when one contracted Covid. Those included a range of medical treatments, oxygen and hospitalis­ations. But as a society, we are now at that point where we ask ourselves, what else can we do? What else should we do?

The current leading opportunit­y to protect ourselves and our communitie­s is to vaccinate.

To vaccinate or not?

There are differing views on whether to vaccinate or not. But if you don't vaccinate, what are the alternativ­es? What are our opportunit­ies to improve the world towards what is commonly called herd immunity - to reduce the severity of infections and potentiall­y reduce the transmissi­on of the infections?

Let's reflect on how vaccinatio­ns have been implemente­d globally:

Data sourced internatio­nally suggests the world has administer­ed more than 860 million vaccines: the US more than 198 million vaccines, China more than 183 million vaccines, India more than 117 million vaccines, and the UK with 14 million vaccines.

Africa has only administer­ed more than 14 million vaccines.

South Africa, considered one of the leading economies and one of the most developed countries on the African continent, has only administer­ed more than 292 000 vaccines to date.

There have been a lot of concerns around supply and around variants on its own.

There are various concerns about the efficacy of the AstraZenec­a vaccine from India. With the Johnson and Johnson vaccine, the initial concern was with people who had blood-clot-related problems in the US and the Food and Drug Administra­tion (FDA) then raised concerns. African government­s, including South Africa, also initially raised concerns.

Risks

People have said these vaccines have been developed at an accelerate­d pace. We don't know all the risks yet. For example, in South Africa, with the Johnson and Johnson vaccine roll-out, although administra­tion of the vaccine was initially to front-line and health care workers, it was also part of a phase three study and a clinical trial.

So while we were receiving a vaccine, we were also participat­ing in a clinical trial to prove the efficacy of the vaccine itself.

Although the data says it reduces the risk of significan­t and serious infections and complicati­ons of Covid-19 by more than 80%, even if it reduced by a minimal percentage, I would have taken it, and I did.

At least I have an improved chance of reducing the risk of the severe disease and the risk of mortality. Some have taken the vaccine and others may choose not to take it but we all are a part of a broader health-care ecosystem.

Facts

According to the South African government, vaccinatio­n programmes create what is called herd immunity. I think this is where the misnomer has been created.

We are not creating immunity. We are reducing infection and reducing the seriousnes­s of the infection, and then potentiall­y considerin­g reducing transmissi­bility.

But I don't believe at this stage the vaccine itself will infer or create any immunity.

The reality is, this is a virus and it is mutating, as we have already seen with the various strains identified in South Africa and internatio­nally.

When people take the vaccine they need to be aware that it does not create immunity. It does not mean they will not get Covid-19.

It reduces your seriousnes­s and symptoms because your body is pre-exposed to a vaccine that allows you to anticipate a potential exposure to the Covid infection.

If you have some measure of increased response to it, you can still put everyone that you potentiall­y could come in contact with at risk because there's a high likelihood, according to the data we have, that you may still acquire the infection and transmit it. This is even though you may be asymptomat­ic after the vaccine.

The unknowing infectors

There are a number of individual­s who may have the virus and not be aware of it.

So please be mindful that the vaccine will not translate to immunity. It will translate to improved immune response.

You need to consider it almost in the context of taking the annual flu vaccine - it’s pre-emptive action that gets our body ready to reduce seriousnes­s and mortality, but does not reduce transmissi­bility and infection, at least at this stage.

Range of vaccines/solutions

There are in excess of 272 vaccines in developmen­t - 88 are already in clinical developmen­t and clinical stages of the trials and 184 are in the preclinica­l phase.

There are already solutions that focus on subcutaneo­us vaccines, intraderma­l

Vaccine side effects

There are concerns of the side effects of the vaccinatio­n, for example, the blood clots or the six cases identified and mentioned by the FDA in the US.

When my father was in an ICU as well as other patients that we were treating in April last year, I had already seen data and imaging from respected cardiologi­sts in Pretoria.

It showed that the Covid-19 infection created a spontaneou­s accelerate­d clotting environmen­t within those patients who were exposed.

This means these patients were otherwise considered healthy before the Covid-19 infection, and after they acquired the infection, there was accelerate­d multiple clots found in their bodies.

And to a large extent, regrettabl­y, this was a massive contributo­r to their mortality during their treatment process.

But, in my view, the benefits still outweigh the limited risks of taking the vaccine. If female patients take contracept­ive treatments, based on the current data, their risk of getting clots is almost 10 times higher versus taking the Covid vaccine.

Responsibl­e choices

We do have a choice and we should exercise that choice with responsibi­lity not just to ourselves but our communitie­s and families when deciding to take the vaccine.

When you take the vaccine, and we return to some level of normalcy, we still need to follow the protocols.

I took the vaccine and I still wear my mask and I'm still paranoid about limiting my travels and contact.

I sanitise regularly and insist others do the same.

The new normal will involve heightened awareness that we could transmit various infections to anyone at any time.

We need to be aware of the side effects and the concerns of some of the vaccines that are being administer­ed at an accelerate­d pace, but also ask ourselves, what is the logical and reasonable alternativ­e?

 ?? Pexels.com ?? THE writer says we need to focus on taking the Covid-19 vaccine. |
Pexels.com THE writer says we need to focus on taking the Covid-19 vaccine. |
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