Safe vac­ci­na­tion

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TAK­ING the quadri­va­lent hu­man pa­pil­lo­mavirus (HPV4) vac­ci­na­tion is not linked with in­creased risk of au­toim­mune dis­or­ders in girls, ac­cord­ing to re­searchers.

While sev­eral stud­ies have in­di­cated the safety of the vaccine, there are con­cerns about a pos­si­ble link to au­toim­mune dis­or­ders, such as lu­pus, rheuma­toid arthri­tis, Type 1 di­a­betes and mul­ti­ple scle­ro­sis.

“In light of th­ese con­cerns, we wanted to study the HPV4 vac­ci­na­tion,” said Jef­frey Kwong, se­nior sci­en­tist at the In­sti­tute for Clin­i­cal Eval­u­a­tive Sciences (ICES).

For the study, pub­lished in the jour­nal in CMAJ (Cana­dian Med­i­cal As­so­ci­a­tion Jour­nal), the team looked at data on 290 939 girls, aged 12 to 17 years, in On­tario.

Of the to­tal 180 819 girls, who re­ceived the HPV4 vac­ci­na­tion in school­based clin­ics, there were

681 di­ag­nosed cases of au­toim­mune dis­or­ders.

This rate is con­sis­tent with the gen­eral rate of di­ag­nosed cases in this age group and adds to the body of ev­i­dence for the safety of the vaccine.

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