Sunday Times

Gingers get the last laugh . . . at long last

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JULIANNE MOORE PEOPLE with red hair have long been the butt of unfair jokes, but a study suggests that when it comes to ageing they may have the last laugh.

Dutch scientists have discovered that a gene that keeps people looking young is the same gene responsibl­e for red hair and fair skin.

Researcher­s at Erasmus University in Rotterdam studied the faces of almost 2 700 elderly Dutch men and women and found that those carrying a variation of the MC1R gene, which influences skin colour, looked on average two years younger than they were.

MC1R is known to play a part in other biological processes, such as inflammati­on and DNA damage repair, which may be why it is linked to youthful looks.

Dr Manfred Kayser, who cowrote the study, said: “For the PRINCE HARRY first time a gene has been found that explains in part why some people look older and others younger for their age.

“Looking young for one’s age has been a desire since time immemorial. The desire is attributab­le to the belief that appearance reflects health and fecundity.”

The findings are particular­ly good news for redheads, as the data suggest they may be ageing slower and therefore be healthier. Perceived age has been shown to predict a person’s health and mortality, suggesting that the age we perceive a person to be from the appearance of their face might also be related in important ways to a person’s biological age and health.

During the study, published in the journal Current Biology, front and side images of the participan­ts’ faces were EMMA STONE analysed by a 3-D image assessment system. It looked at more than 25 criteria, such as pigmented spots, wrinkles, skin tone and face shape.

This informatio­n was then subjected to an algorithm, which came up with a perceived age. Kayser said that understand­ing the molecular biology of perceived age would be vital in identifyin­g new ageing therapies, among other purposes.

“Our study provides new leads for further investigat­ing the biological basis of how old RUPERT GRINT or young people look,” he said.

The associatio­n between the MC1R variant and perceived age found by the Erasmus University study has been replicated in two independen­t cohorts, including a study of 530 middle-aged French women, which also linked the gene to skin ageing.

The authors of the latest research said more investigat­ion was needed to identify precisely how specific features, such as skin sag or skin repair, could be linked to MC1R.

Dr David Gunn, of Unilever, which participat­ed in the study, said: “The perception of age is one of the best and most exciting ways to measure how well people are ageing, which we hope will lead to further breakthrou­ghs in health and ageing research.”

Looking young for one’s age has been a desire since time immemorial

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