Sunday Times

Vaping may take a hit from Juul crisis

Firm’s misbehavio­ur risks crackdown on alternativ­e to smoking

- By JOHN GAPPER

● The crisis at the US vaping group Juul that contribute­d to the collapse of a possible $200bn (R3-trillion) merger between Altria and Philip Morris Internatio­nal is another example of a fashionabl­e disrupter of a traditiona­l industry faltering.

WeWork has shelved its initial public offering and Juul’s $38bn valuation is evaporatin­g.

But Juul’s troubles, which led to its CEO being replaced last week, are not merely a financial shock to its investors. The company’s misbehavio­ur could cause public health damage by sparking a broad US crackdown on the best alternativ­e to smoking apart from giving up nicotine entirely.

The US is in danger of lurching from an overly permissive approach, which encouraged vaping to spread among teenagers, to barring e-cigarettes. Asian countries are already imposing bans.

Neither is the best way to regulate vaping and to wean citizens off their dangerous addiction to tobacco.

The trouble started with a teenage craze that led to 21% of US high school students inhaling nicotine through devices at least occasional­ly last year. Like other countries, the US prohibits television and other kinds of advertisin­g for cigarettes, but it allowed Juul and others to advertise e-cigarettes widely, and to enlist celebritie­s and social media influencer­s.

The damage done by this loophole was compounded by lax regulation. Juul was permitted to sell higher-strength pods in the US than in Europe and to add flavours.

Though US retailers are barred from selling e-cigarettes to under-18s, 80% of Juul’s US sales are estimated to come from teenfriend­ly flavours such as mint.

It became a crisis with the discovery of 805 (and counting) cases of unexplaine­d lung injuries among vapers, including 12 deaths in 10 states.

That led to a warning by the US Centers for Disease Control and Prevention (CDC) for all Americans to consider stopping vaping. Walmart has stopped selling e-cigarettes, San Francisco has prohibited sales and states are leaping into action.

Parents are understand­ably worried about their children becoming addicted to nicotine, and fears are growing that vaping will turn out to be like cigarette smoking: a habit that seemed benign in the early days, but turned out to be very dangerous.

About 480,000 people die every year in the US from smoking-related diseases.

But nicotine vaping does not appear to be the cause of most of the recent lung injuries. The CDC disclosed on Friday last week that 77% of the cases it analysed involved people who had used devices to inhale the cannabis compound THC.

THC is often mixed by street sellers of cannabis vapes with vitamin E acetate, an oil that can irritate the lungs and cause a form of pneumonia.

Only 16% of patients claimed to have inhaled only nicotine vapour, which is waterbased and contains few chemicals, compared with an estimated 7,000 chemicals in tobacco smoke.

“There is some risk with nicotine vaping but the health benefits of reducing smoking hugely outweigh it,” says John Britton, director of the UK Centre for Tobacco and Alcohol Studies.

The UK’s Royal College of Physicians estimates that nicotine vaping could carry 5% of the health risk of smoking in the long term. This is equivalent to 24,000 deaths per year in the US if every smoker vaped instead (and had never smoked). It would be a heavy toll, but tiny compared with smoking.

The best public health outcome remains to persuade as many adult smokers as possible either to give up cigarettes, or limit their risk by switching to vaping nicotine from regulated suppliers.

That means keeping e-cigarettes available for sale while trying to prevent young people from taking up vaping and becoming addicted to nicotine, with the risk of later turning to smoking.

This strategy has worked quite well in European countries including the UK, despite the US crisis. Cigarette smoking is in longterm decline, and while 3.6-million British people now vape, only 6% of them never smoked. Meanwhile, only 1.6% of 11- to 18year-olds vape more than once a week.

Unlike in the US, e-cigarette advertisin­g is banned in Europe and an EU directive in 2014 set stricter standards for the regulation of vaping. European countries including Finland have barred flavours, and regulators have not faced the same political backlash as the US Food and Drug Administra­tion (FDA).

The FDA has changed course under pressure. It wrote a warning letter to Juul last month asking it to justify claims that vaping is safer than smoking and accusing it of ignoring the law.

That prompts the question of why the FDA has not found out for itself, and why so much marketing was allowed.

The danger is that the US compensate­s for past laxity and cracks down so heavily that it snuffs out proper uses for e-cigarettes. Vaping companies face a deadline of May next year to submit existing products for approval.

Outlawing vaping would be easy, but the side effect would be heavier smoking.

Amid fears about the spread of teen vaping, it is easy to miss another vital statistic: the number of US adult cigarette smokers fell by 9% in 2017 as people gave up or found alternativ­es. Something is going right.

Some risk with nicotine vaping but the health benefits of reducing smoking hugely outweigh it John Britton

Director, UK Centre for Tobacco and Alcohol Studies

 ?? Picture: Alaister Russell ?? Vaping is not ideal, but as the next best thing to giving up smoking entirely, it is thought to save many lives.
Picture: Alaister Russell Vaping is not ideal, but as the next best thing to giving up smoking entirely, it is thought to save many lives.

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