Sunday Times

Ventilator toll ‘not conclusive’

- By CLAIRE KEETON

● A snapshot of mortality among Covid-19 patients on ventilator­s in SA is sobering, but too small and incomplete to provide a reliable picture of patient survival.

Most people with Covid-19 who go onto mechanical ventilator­s will die, internatio­nal studies show. “Outcomes internatio­nally have shown mortality rates of 60% to 95% in many countries, including the US, China and Italy,” said Wits University infectious diseases specialist Dr Jeremy Nel.

The National Institute for Communicab­le Diseases Covid-19 hospital sentinel surveillan­ce report found that nine out of 10 patients ventilated in public hospitals die.

It found that the death rate in private hospitals was a lower 30%. This does not match global trends and Nel said the outcome was probably because the sample of 61 was too small and the time period too short.

“Almost half the ventilated patients in the private sector data were still on a ventilator at the time the statistics were calculated, and so the number of deaths in this group can be expected to rise with time,” he said.

“The numbers reported from the state sector are very small at this point, and so drawing firm conclusion­s isn’t wise. In addition, the surveillan­ce data is not comprehens­ive — many hospitals aren’t yet included — and so the results of the surveillan­ce may not be generalisa­ble across the country.”

Professor Guy Richards, director of critical care at Charlotte Maxeke Johannesbu­rg Academic Hospital, said the management of Covid-19 patients in both public and private hospitals in Gauteng followed a similar approach.

“Essentiall­y, we try to avoid mechanical ventilatio­n,” he said, listing critical steps, including high-flow nasal oxygen, they would take to treat Covid-19 admissions before ventilatio­n might become necessary.

“If multi-organ failure ensues or prolonged mechanical ventilatio­n is required, then mortality increases exponentia­lly.”

Doctors in the Western Cape are starting to record promising results from “proning” — positionin­g seriously ill patients on their stomachs — and using high-flow oxygen rather than putting them on ventilator­s.

The health of patients being admitted to public hospitals often does not compare to those insured patients being admitted to private hospitals, doctors noted, making comparison­s between patient outcomes unscientif­ic. “The socioecono­mic conditions of population­s are totally different between public and private hospitals,” said professor Landon Myer, head of the University of Cape Town school of public health and family medicine. “Private has the wealthiest, healthiest 15% to 20%, while 85% of people are in public health care, which has the higher burden of disease.”

Co-morbiditie­s are common among patients relying on public hospitals, and intensive care unit beds are scarcer per patient given their limited resources.

“For those patients, the disease has to be quite severe but there also has to be a chance of survival, to help ensure scarce resources are used optimally,” said Myer.

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Guy Richards

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