Sunday Times

World, look to Africa

Our scientists must not practise in isolation, but be encouraged to be creative and increase our knowledge of the needs of developing economies

- By MAMOKGETHI PHAKENG and THOKOZANI MAJOZI

Our continent must collaborat­e in vaccine trials

● Whenever solutions are sought to some of the most crucial problems confrontin­g humankind, seldom does the world face in the direction of Africa. This is particular­ly true in science, engineerin­g and technology.

Most of the solutions to African problems remain largely of Western origin, which has wittingly or unwittingl­y earned Africa the reputation of a net consumer of knowledge. In ways akin to the legendary Chinua Achebe’s magnum opus, Things Fall Apart, this situation does not bode well for Africa.

A sparely told tale that is consonant with universal realities, Things Fall Apart is set in pre-British colonial-era Nigeria and tells a story of a heroic man called Okonkwo. He has exceptiona­l physical strength, is an exemplary family man and a successful farmer. His achievemen­ts are hard won and through his leadership, his village is seemingly at peace, neatly interwoven and loyal to its tribal norms.

Okonkwo commits a terrible crime and is exiled for seven years. In his absence, British colonialis­m sets in, bringing an end to traditiona­l and coherent tribal life. Okonkwo returns but nothing is ever the same.

It may be argued that Africa is partly to blame for the repercussi­ons of its absence from the global stage — from being in subtle spectator roles where Africans should be players, to the sheer levity of those who see themselves as saviours of the continent.

A case in point is the live broadcast on French TV in April of two senior French doctors discussing the possibilit­y of testing the BCG tuberculos­is vaccine’s potential effectiven­ess against Covid-19 in African population­s. They compared Africans to prostitute­s in historic HIV studies, ostensibly because Africans are highly exposed and “do not protect themselves”.

This sparked outrage and a lukewarm apology followed. But the damage had been done.

Africans took umbrage at being seen as guinea pigs. This was expected. What was not expected were proclamati­ons that suggested an African-only, rather than an African-led, approach in finding the vaccine.

At best this would pull Africa further from the global stage. At worst, it would stifle growth and reverse all gains made in science on the continent.

History has taught us that any science advanced along boundary lines is doomed. SA has first-hand experience. In 1953, the chief architect of apartheid, Hendrik Verwoerd, posed a question in parliament, “What is the point of teaching a bantu [black] child mathematic­s when he cannot use it in practice?” This meant most of the population had to be excluded from almost all advances in science. The repercussi­ons haunt us to this day.

It would be tragic if Africa chose not to take part, at all levels, in clinical trials of a Covid-19 vaccine — or any medical treatment that could save lives.

Africans, too, are susceptibl­e to Covid-19, whether involved in vaccine trials or not. In April, Inserm, the French National Institute of Health and Medical Research, told the BBC that clinical trials to test the efficacy of the BCG vaccine against Covid-19 were about to be launched in Western countries. It said: “Africa must not be forgotten or excluded.” We must bury the notion that “global” is “not African”.

There are sound medical reasons for testing such a vaccine in different communitie­s, including lowincome countries. Experience has demonstrat­ed that humans in different countries may have different underlying conditions that cause them to respond differentl­y to vaccine candidates. It has been found that a virus may develop different strains in different population­s. So a vaccine that is effective in Europe may be less so in Africa or South America.

The absence of developing nations from Covid-19 treatment trials around the world is a concern. Nature reported on April 3 that of about 300 clinical trials for a Covid-19 vaccine, most were in China and South Korea, with Europe and the US close behind. Few are taking place in Africa, Latin America and Southeast Asia, where the virus could surge next.

The World Health Organisati­on has called for more African nations to participat­e in its Solidarity trial, a global study of four potential Covid-19 treatments. Researcher­s are urging faster action in countries with ill-equipped health systems, in which SA is participat­ing.

Covid-19 is an opportunit­y for African scientists to provide insights to the characteri­stics of the virus and effective strategies for its treatment. This opportunit­y would be lost if Africans were to practise in isolation. That would risk encouragin­g African scholars and researcher­s to migrate to global projects and slow down research at our universiti­es and government laboratori­es that could save lives, create jobs and businesses, and develop African economies. This can promote African creativity and increase our knowledge of the needs of developing economies.

We risk extending poverty and inequality by slowing down research into these challenges. We compromise opportunit­ies for African researcher­s and scientists to learn the technologi­es and techniques of the Western world as they develop capacity in Africa. We are seeing niche sectors developing as a result of co-operation such as drug discovery and developmen­t.

The Internatio­nal Science Council, which is led by professor Daya Reddy of SA and comprises about 180 different science councils, academies and organisati­ons around the world, was founded to encourage such collaborat­ion, to stimulate and support internatio­nal scientific research and scholarshi­p, communicat­e science that is relevant to internatio­nal policy issues, and enable science to contribute more effectivel­y to major issues. Scientists recognise the value of working together to overcome hazards humanity faces.

There can be no substitute for collaborat­ion.

Phakeng is the vice-chancellor of the University of Cape Town and a professor in mathematic­s education. Majozi is a professor of chemical engineerin­g at the University of the Witwatersr­and, where he holds the NRF-DST chair in sustainabl­e process engineerin­g, and is the chairman of the CSIR board

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 ?? Picture: Adrienne Surprenant/Bloomberg via Getty Images ?? A magnified coronaviru­s illustrati­on at the Pasteur Institute in France. The writers say that African scientists need to work with the world on a vaccine.
Picture: Adrienne Surprenant/Bloomberg via Getty Images A magnified coronaviru­s illustrati­on at the Pasteur Institute in France. The writers say that African scientists need to work with the world on a vaccine.

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