SCIENTISTS are considering a number of different HIV vaccine designs, namely:
Live vector vaccine: non-HIV viruses that have been engineered to carry HIV genetic material. The HIV genes are inserted into the virus that has been deactivated, so it is not dangerous. This is called a vector and it carries the genes into the body’s cells. The smallpox vaccine, use this approach.
Peptide vaccine: made of tiny pieces of proteins from the HIV virus.
Recombinant protein vaccine: made of bigger pieces of proteins that are on the surface of the HI virus.
DNA vaccine: uses copies of a small number of HIV genes that are inserted into pieces of DNA called plasmids. The HIV genes produce proteins very similar to the ones from real HIV.
Vaccine combination: uses any two vaccines, one after another, to create a stronger immune response – often referred to as “prime-boost strategy.”
Virus-like particle vaccine (pseudovirion vaccine): a non-infectious HIV lookalike that has one or more, but not all, HIV proteins.