The Citizen (Gauteng)
Africa wants own vaccine
PLANTS: CALL FOR MANUFACTURE ON CONTINENT US supports waiver of intellectual property for Covid shots.
Rwanda, South Africa, and Senegal are among countries calling for the establishment of full vaccine-manufacturing plants to prepare for future pandemics after Africa found itself at the back of the queue for Covid-19 shots.
While many developed nations are well advanced with their vaccination rollouts, most African countries are almost out of initial supplies and the continent accounts for just 2% of global administered shots, data from the Africa Centres for Disease Control and Prevention show.
There are fewer than 10 vaccine manufacturers in Africa, based across Egypt, Morocco, Tunisia, Senegal, and South Africa, according to the World Health Organisation. Most of those carry out packaging and labelling rather than manufacturing. That makes the continent illequipped to source and supply doses in times of crisis.
“The only way to ensure vaccine equity is to produce more vaccines where they are needed,” Rwanda President Paul Kagame said this week. “So long as Africa remains dependent on other regions for vaccines, we will always be at the back of the queue whenever there is scarcity.”
Among the biggest barriers to local manufacturing are intellectual-property protections. Almost 100 developing countries, led by India and SA, have petitioned for a waiver and the sharing of recipes for Covid-19 doses, but that’s been opposed by some nations and drugmakers.
The US changed its stance to back the proposal this week, opening the door to negotiations between members of the World Trade Organisation.
The campaign “is understandable given past and present experience of waiting in line to get life-saving medications and vaccines”, Ngozi Okonjo-Iweala, director-general of WTO, said. WTO members “must increase vaccine production now and also look for pragmatic outcomes” to the intellectual-property protection issue.
Vaccine manufacturing needs both significant financing and specialised skills to build factories that can be certified as free from contamination, said Stavros Nicolaou, chairman of South Africa’s local pharmaceutical manufacturers industry association.
“These skills and expertise are in limited supply on the continent,” he said. “It is possible to build further fill-and-finish capacity, but this requires local manufacturers having guaranteed off-takes and ongoing demand.”
The BioVac Institute, a statebacked South African vaccine company, has won a deal with US-based ImmunityBio to make coronavirus shots if that company’s vaccine is approved. It expects a new plant to cost as much as €200 million (R3.4 billion).
In Ghana, the pharma industry body has also proposed a local factory, but says it could take as long as two years to complete.
BioVac currently runs a fill-finish site, allowing it to package doses, but now wants to build a plant that produces the ingredients needed for the vaccines themselves. Aspen Pharmacare signed a deal with Johnson & Johnson to fill and finish its version of the Covid-19 vaccine locally.
“The current Covid-19 pandemic presents a great opportunity to harness the various conversations and proposals into an action-oriented road map,” said William Ampofo, chair of the African Vaccine Manufacturing Initiative. –
We will always be at the back of the queue