The Mercury

‘Oestrogen may be why fewer women die from Covid-19’

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R%#%)6).' hormone replacemen­t therapy within six months of a RECORDED DIAGNOSIS OF #OVID was associated with a reduction in mortality from the infectious disease among women, finds a study indicating the role of oestrogen in fighting the deadly virus.

While men and women are EQUALLY SUSCEPTIBL­E TO THE 3ARS #O6 virus, men tend to have more severe infections and have higher rates of hospitalis­ation and mortality.

A recent review of sex difference­s IN #OVID USING DATA FROM countries, found mortality in men WAS TIMES HIGHER THAN IN WOMEN Younger women or those with higher oestrogen levels are less

LIKELY TO EXPERIENCE #OVID complicati­ons.

Earlier studies have also shown that women have faster and greater immune responses to viral infections.

Researcher­s have observed similar data in previous pandemics, INCLUDING THE 3ARS #O6 3EVERE !CUTE Respirator­y Syndrome Coronaviru­s) AND -%23 #O6 -IDDLE %AST Respirator­y Syndrome Coronaviru­s) outbreaks.

Although the reason for these sex difference­s is uncertain, limited recent observatio­nal data suggest that oestrogen may reduce the SEVERITY OF #OVID DISEASE

The new study, led by researcher­s at the University of Southampto­n in the UK, showed that hormone replacemen­t therapy (HRT) was ASSOCIATED WITH A REDUCTION IN ALL CAUSE MORTALITY IN #OVID

HRT is a medication to replace the oestrogen that the human body stops making during menopause.

The finding suggests that oestrogen may well contribute to a protective effect against Covid severity.

This may explain why fewer women compared to men have been hospitalis­ed, admitted to intensive CARE OR DIED DUE TO #OVID DURING the pandemic.

“This study supports the theory that oestrogen may offer some PROTECTION AGAINST SEVERE #OVID v said Christophe­r Wilcox from the university.

The study, published by Oxford University Press in the journal Family Practice, investigat­ed the associatio­n between hormone replacemen­t therapy or combined oral contracept­ion use and the likelihood of death in women with #OVID

Researcher­s investigat­ed combined oral contracept­ion, which contains oestrogen because some recent observatio­nal data suggests that women taking oral contracept­ives have a lower risk of ACQUIRING #OVID

They identified a group of

WOMEN OVER IN %NGLAND 4HERE WERE #OVID cases within the cohort.

Wilcox noted that the study provides “reassuranc­e to patients and clinicians that there is no indication to stop hormone replacemen­t therapy because of the pandemic”.

This comes even as Britain is experienci­ng an acute shortage of HRT, which is used by about one million women in the UK, owing to an increase in demand.

 ?? A YOUNG girl is vaccinated at Sefako Makgatho Health Sciences University. | THOBILE MATHONSI African News Agency (ANA) ??
A YOUNG girl is vaccinated at Sefako Makgatho Health Sciences University. | THOBILE MATHONSI African News Agency (ANA)

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