The Star Late Edition

Decrease foreign pharmaceut­ical imports

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THE 12th Internatio­nal Aids Society Conference on HIV Science was recently held in Brisbane, featuring a number of studies that have come to represent important advances in HIV prevention, treatment and cure research.

The conference offered the WHO an opportunit­y to announce that there is negligible, or almost zero risk of transmitti­ng HIV when a person has a suppressed viral load.

These findings have underscore­d the significan­ce of meeting UNAids “95-95-95” targets, which call for 95% of people living with HIV to be aware of their status, 95% of those aware of their status to be on antiretrov­iral therapy (ART), and 95% of those on ART to achieve viral load suppressio­n.

WHO’s scientific research must incentivis­e public and private stakeholde­rs to work together to spearhead the developmen­t of Africa’s pharmaceut­ical and biological manufactur­ing framework if we want to improve our ability to prevent, detect and limit the transmissi­on of the virus at its epicentre.

In order to achieve this, we must decrease our reliance on foreign pharmaceut­ical imports by securing Africa’s own supply of lifesaving ARVs over the long-term. African scientists must be supported to develop their own intellectu­al property for developing active pharmaceut­ical ingredient­s (API) if we want to build an end-to-end manufactur­ing framework on the continent.

Investing (locally) in a biologics facility with the capacity to manufactur­e APIs and supply PrEP injectable­s will also remain a significan­t undertakin­g. If we can develop the technology and APIs to manufactur­e PrEP locally, with other mRNA based products, South Africa could position itself at the forefront of this initiative. The world-renowned Afrigen Biologics mRNA hub in Cape Town, already aims to contribute significan­tly to this initiative.

We will have to leverage the expertise of our closest allies and make use of all grant-funding opportunit­ies to make this a reality. Perhaps South Africa, with its intellectu­al capacity and infrastruc­ture, can lead the charge to improve medicine and vaccine supply security for the whole continent – soon.

MICHAEL MYNHARDT | Group Executive & Business Strategist

 ?? Supplied ?? IF WE can develop the technology and APIs to manufactur­e PrEP locally, with other mRNA based products, South Africa could position itself at the forefront of this initiative, says the writer. |
Supplied IF WE can develop the technology and APIs to manufactur­e PrEP locally, with other mRNA based products, South Africa could position itself at the forefront of this initiative, says the writer. |

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