Daily Mirror (Sri Lanka)

Research uncovers underlying mechanisms behind ‘COVID Toes’


Redness and swelling of the hands and toes, known as chilblain-like lesions, have been reported during the COVID-19 pandemic.a new study published in the British Journal of Dermatolog­y uncovers the underlying mechanisms involved in such “COVID toes” symptoms.

The study included 50 participan­ts with COVID toes and 13 with similar chilblains lesions that arose before the pandemic. The mechanisms behind both types involved an immune response with high levels of certain autoantibo­dies as well as type I interferon, a key protein in the antiviral response. In addition to the immune system, endothelia­l cells that line blood vessels also appeared to play a critical role in the developmen­t of COVID toes and chilblains.

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