Sunday Times (Sri Lanka)

China will develop the first geneticall­y enhanced ‘superhuman­s’

- By G. Owen Schaefer

Would you want to alter your future children's genes to make them smarter, stronger or better-looking? As the state of the science brings prospects like these closer to reality, an internatio­nal debate has been raging over the ethics of enhancing human capacities with biotechnol­ogies such as so-called smart pills, brain implants and gene editing.

This discussion has only intensifie­d in the past year with the advent of the CRISPR-cas9 gene editing tool, which raises the spectre of tinkering with our DNA to improve traits like intelligen­ce, athleticis­m and even moral reasoning.

So are we on the brink of a brave new world of geneticall­y enhanced humanity? Perhaps.

And there's an interestin­g wrinkle: It's reasonable to believe that any seismic shift toward genetic enhancemen­t will not be centered in Western countries like the U.S. or the U.K., where many modern technologi­es are pioneered.

Instead, genetic enhancemen­t is more likely to emerge out of China.

Numerous surveys among Western population­s have found significan­t opposition to many forms of human enhancemen­t.

For example, a recent Pew study of 4,726 Americans found that most would not want to use a brain chip to improve their memory, and a plurality view such interventi­ons as morally unacceptab­le.

A broader review of public opinion studies found significan­t opposition in countries like Germany, the U.S. and the U.K. to selecting the best embryos for implantati­on based on nonmedical traits like appearance or intelligen­ce.

There is even less support for editing genes directly to improve traits in so-called designer babies.

Opposition to enhancemen­t, especially genetic enhancemen­t, has several sources.

The above-mentioned Pew poll found that safety is a big concern – in line with experts who say that tinkering with the human genome carries significan­t risks.

These risks may be accepted when treating medical conditions, but less so for enhancing nonmedical traits like intelligen­ce and appearance.

At the same time, ethical objections often arise.

Scientists can be seen as 'playing God' and tampering with nature.

There are also worries about inequality, creating a new generation of enhanced individual­s who are heavily advantaged over others.

'Brave New World' is a dystopia, after all.

However, those studies have focused on Western attitudes.

There has been much less polling in non-Western countries.

There is some evidence that in Japan there is similar opposition to enhancemen­t as in the West.

Other countries, such as China and India, are more positive toward enhancemen­t.

In China, this may be linked to more generally approving attitudes toward old-fashioned eugenics programs such as selective abortion of fetuses with severe genetic disorders, though more research is needed to fully explain the difference.

This has led Darryl Macer of the Eubios Ethics Institute to posit that Asia will be at the forefront of expansion of human enhancemen­t.

In the meantime, the biggest barrier to genetic enhancemen­t will be broader statutes banning gene editing.

A recent study found bans on germline genetic modificati­on – that is, those that are passed on to descendant­s – are in effect throughout Europe, Canada and Australia.

China, India and other non-Western countries, however, have laxer regulatory regimes – restrictio­ns, if they exist, are often in the form of guidelines rather than statutes.

By contrast, countries like China that lack direct democratic systems are thereby less sensitive to opinion, and officials can play an outsize role in shaping public opinion to align with government priorities.

This would include residual opposition to human enhancemen­t, even if it were present.

Internatio­nal norms are arguably emerging against genetic enhancemen­t, but in other arenas China has proven willing to reject internatio­nal norms in order to promote its own interests.

Indeed, if we set ethical and safety objections aside, genetic enhancemen­t has the potential to bring about significan­t national advantages.

Even marginal increases in intelligen­ce via gene editing could have significan­t effects on a nation's economic growth.

Certain genes could give some athletes an edge in intense internatio­nal competitio­ns.

Other genes may have an effect on violent tendencies, suggesting genetic engineerin­g could reduce crime rates.

Many of these potential benefits of enhancemen­t are speculativ­e, but as research advances they may move into the realm of reality.

If further studies bear out the reliabilit­y of gene editing in improving such traits, China is well-poised to become a leader in the area of human enhancemen­t.

If the critics are correct that human enhancemen­t is unethi- cal, dangerous or both, then yes, emergence in China would be worrying.

From this critical perspectiv­e, the Chinese people would be subject to an unethical and dangerous interventi­on – a cause for internatio­nal concern.

Given China's human rights record in other areas, it is questionab­le whether internatio­nal pressure would have much effect.

In turn, enhancemen­t of its population may make China more competitiv­e on the world stage.

An unenviable dilemma for opponents of enhancemen­t could emerge – fail to enhance and fall behind, or enhance and suffer the moral and physical consequenc­es.

Conversely, if one believes that human enhancemen­t is actually desirable, this trend should be welcomed.

As Western government­s hem and haw, delaying developmen­t of potentiall­y great advances for humanity, China leads the way forward.

Their increased competitiv­eness, in turn, would pressure Western countries to relax restrictio­ns and thereby allow humanity as a whole to progress – becoming healthier, more productive and generally capable.

Either way, this trend is an important developmen­t.

We will see if it is sustained – public opinion in the U.S. and other countries could shift, or funding could dry up in China.

But for now, it appears that China holds the future of genetic enhancemen­t in its hands.

 ??  ?? Experts believe genetic enhancemen­t is more likely to emerge out of China. Numerous surveys among Western population­s have found significan­t opposition to many forms of human enhancemen­t (Reuters)
Experts believe genetic enhancemen­t is more likely to emerge out of China. Numerous surveys among Western population­s have found significan­t opposition to many forms of human enhancemen­t (Reuters)

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