Sunday Times (Sri Lanka)

Lanka’s first-ever TAVI at NHSL

70-year-old saved from death through Transcathe­ter Aortic Valve Implantati­on by heart team headed by Dr. Sepalika Mendis

- By Chrishanth­i Christophe­r By Kumudini Hettiarach­chi

The Plantation­s Ministry has said a gazette notice confining the use of glyphosate only to rubber and tea plantation­s will be issued next week.

Plantation Ministry Secretary J.A. Ranjith said the notice is with the government printer and will be released on September 15, 2018.

‘The weedicide will be distribute­d soon,’ he said.

Imports will depend on the needs of Regional Plantation Companies and the Small Holding Companies. The Ceylon Petroleum Corporatio­n will be the sole importer.

Distributi­on will be done through the Tea Research Institute and the Small Holding Developmen­t Authority.

In 2015, the government banned glyphosate over the fear of chronic kidney disease among farmers in the North Western Province and elsewhere. The Registrar of Pesticide rescinded the

It was a cherished dream for a Senior Consultant Cardiologi­st and for the humble people of Sri Lanka suffering and dying from heart trouble, it is a great blessing. For the country, it is a major groundbrea­ker – Transcathe­ter Aortic Valve Implantati­on (TAVI) is now very much a reality, not after payment of a large fee in the private sector but in the absolutely free state sector at the National Hospital of Sri Lanka (NHSL).

Before we get the details of the first-ever TAVI procedure from Senior Consultant Cardiologi­st Dr. Sepalika Mendis of the NHSL’s Institute of Cardiology, it is a chat with the flag-bearer patient, E.M. Prema Seram (70). Two others who underwent the procedure after her have been discharged, but Prema is in the Coronary Care Unit (CCU) yet because her blood sugar levels have been slightly high and Dr. Mendis wants to make sure that it is well controlled.

Grey-haired Prema from Kadawatha is all smiles because she did not think that she would come out of the last episode when she had severe breathing difficulti­es.

“Merila wage genawe,” says husband Upali K. Perera just before we meet Prema, reliving the trauma of the close shave that she faced. As their son and granddaugh­ter nod in agreement, he tells the Sunday Times how Prema got papuwe amaruwa (chest trouble) about three years ago, with severe breathing difficulti­es. They rushed her to the Colombo North Teaching Hospital, Ragama, where an echocardio­gram was done and they were advised to seek treatment from the NHSL.

At the Institute of Cardiology, it was in December 2017 that a coronary angiogram (X-ray imaging, after sending a dye, to see whether there is a restrictio­n in the heart's blood vessels) was performed.

There was one block in the Left Anterior Descending Artery for which Dr. Mendis did stenting (inserting a tiny tube to keep the blocked vessel open).

There was also a serious issue with a heart valve – the aortic valve, the “main gate”, between the aorta and the heart’s left ventricle was clogged. The aorta is the largest artery in the body which begins at the top of the heart’s left ventricle to supply blood to all parts of the body.

Prema was suffering from aortic stenosis, a common but very serious valve disease. This narrowing of the aortic valve opening not only restricts the blood flow from the left ventricle to the aorta but also affects the pressure in the left ventricle.

Three times Prema had gone into left the Sunday Times ventricula­r failure and was looked after in the Coronary Care Unit (CCU) of the Institute of Cardiology by Dr. Mendis’s team whom she calls “excellent”.

Finally, as her husband says, “nethiwena size ekatama awa” (came close to losing her) and open heart surgery was a clear “no, no” because the aortic stenosis had also affected her lungs and Prema herself refused pointblank to do so.

Amidst the despair though shone a beam of hope with Dr. Mendis offering a “brand new” procedure for Prema and also for Sri Lanka.

As Upali and their son paced the cor- ridors outside the Catheteriz­ation Laboratory on Sunday, September 2, and lots of doctors converged on the Institute of Cardiology, Dr. Mendis set about performing the very first TAVI in Sri Lanka, becoming a trailblaze­r along with her team.

“Prema was a high risk patient,” says Dr. Mendis, explaining that when she came in for the third time she was critically ill. She checked her stent and it was patent ( working) and then sent her to Ward 61. There Prema developed breathless­ness and went into acute heart failure, being rushed to the CCU to be intubated and ventilated to help her breathe.

For Dr. Mendis who has been at the NHSL for 26 long years, starting as a Senior Registrar (SR) here, the structure of the heart has always fascinated her. It was as an SR under Dr. Nihal Thenabadu that she assisted in the first Aortic Valvular Plasty and more.

There has been no turning back since then for Dr. Mendis – whether it was the closure of an atrial septal defect or ventricula­r septal defect (ASD or VSD – holes in the heart) through catheteriz­ation.

The Sunday Times understand­s that the first Patent Ductus Arteriosus device closure was performed by Dr. Mendis. (PDA is an abnormal blood flow between two of the major arteries connected to the heart.)

Having also performed Left Atrial Appendage closure, Dr. Mendis had been wondering what next she could do for the benefit of patients before she puts down her scalpel in the state sector when she retires in a few years.

TAVI was what came to mind, as in 2016 Dr. Mendis along with then Resident Cardiologi­st Dr. Prakash Priyadhars­han and SR Dr. Charitha Herath had closed a large aortic aneurysm using a device in a patient who had undergone bypass surgery in an open heart operation. The aneurysm was eroding into the bronchus and the sternum (breastbone) and surgeons had refused to undertake open heart surgery as it was high risk.

In October 2016, she applied to present a paper at a conference in San Francisco, America, where she and her junior, Dr. Herath, looked at, touched and stroked numerous valves to see what would be best suited for Sri Lanka. Even though they attempted to locate the agent who was supplying these valves to Asia they failed but in a fortuitous coincidenc­e her junior had shared a taxi with him when he was on his way to the airport to fly back to Sri Lanka.

However, Dr. Mendis knew what the challenges were -- not only did she need training in aortic valve procedures, she also had to have a good cath lab and a good team along with surgical backing.

The world renowned experts on TAVI were based in Hungary and one of them was Cardiologi­st Dr. Geza Fontoz and Dr. Mendis was wondering how she could pick his brain on how to select patients and how to get about the procedure when she heard that he would be in Chennai, India, for a conference.

In preparatio­n for the first TAVI, early this year Dr. Mendis had meanwhile organized a workshop, talking to Cardiac Surgeons all over the country to help her find patients with aortic valve stenosis. They had obligingly found 70 patients and her team had worked very hard, doing thorough assessment­s after performing coronary angiograms and keeping meticulous lists of contact details, to narrow down the numbers to 30 with pure aortic stenosis, leaving out those with coronary disease.

Of these, 19 seemed ideal candidates and Dr. Mendis had negotiated with a private hospital as the NHSL did not have the facilities for CT aortograms, to get them done at a subsidized rate. C o n s u l t a n t C a rd i o l o g i s t D r. Priyadhars­han had very willingly performed the CT aortagrams.

Armed with all this informatio­n and files of blue and pink that her team had scrupulous­ly put together Dr. Mendis had then flown to Chennai to seek the advice of Dr. Fontoz.

Four cases had been chosen as the flag-bearers with Prema being right in front.

Paying strong tribute to the team which was by her side during the first TAVI, Dr. Mendis says that it included Resident Cardiologi­st Dr. Anidu Pathirana, Consultant Cardiothor­acic Anaestheti­st Dr. Kumudini Ranatunga, Senior Cardiothor­acic Surgeon Dr. Chandima Amarasena, Consultant Cardiologi­st Dr. Prakash Priyadhars­han, Senior Registrar in Cardiology Dr. Rayno Navinan, Electrophy­siologist Dr. Keerthi Diwulveva, Master- in- Charge of the Cardiac Cath Lab Aruna Suraweera, Nursing Of f i c e r S hya m a l e e, Radiograph­er Rajitha Palinda Bandara, ECG Technician­s Hasitha and Dhammika and the NHSL’s Professori­al Unit for providing vascular cover.

Senior Registrars Dr. Sumudu Wickramasi­nghe, Dr. Ambiga Kadiragama­nathan and Dr. Tharanga Fernando had also worked tirelessly.

Pointing out that Health Minister Dr. Rajitha Senaratne encouraged the launch of the new procedure and provided valves, she says that immense support also came from the Director-General of Health Services Dr. Anil Jasinghe, NHSL’s Acting Director Dr. Kumara Wickramasi­nghe, the NHSL’s Deputy Directors and the Heart Associatio­n of Sri Lanka along with NHSL’s Cardiothor­acic Surgeons including Dr. Iresh Wijemanna and Cardiothor­acic Anaestheti­sts including Dr. Malika de Silva, Cardiologi­sts, Electrophy­siologists, Critical Care Consultant­s, Senior Registrars, Medical Officers and other categories of staff.

Meanwhile, to the “dosthara nona” who pulled Prema from the jaws of death, the ever-grateful family will keep showering blessings of sathara warang deviyo. Dr. Sepalika Mendis will not only be in their hearts every waking minute of the day but also in their minds.

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 ??  ?? The TAVI procedure pioneering team at the Institute of Cardiology of the NHSL
The TAVI procedure pioneering team at the Institute of Cardiology of the NHSL
 ??  ?? Dr. Sepalika Mendis, assisted by her team, performing the first-ever TAVI in Sri Lanka
Dr. Sepalika Mendis, assisted by her team, performing the first-ever TAVI in Sri Lanka
 ??  ?? The enmeshed valve used in TAVI procedures
The enmeshed valve used in TAVI procedures
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 ??  ?? Dr. Sepalika Mendis
Dr. Sepalika Mendis

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