Bangkok Post

The importance of testostero­ne

- DR NITHI MAHANONDA Dr Nithi Mahanonda is a consultant cardiologi­st and interventi­onist at Perfect Heart Institute, Piyavate Hospital. Visit his website at www.drnithi.com.

Recent research has shown a link between testostero­ne levels and men’s health. When testostero­ne levels are low, an array of diseases and health problems are often present.

According to research conducted in 2,100 men, aged over 45 years, it was found low testostero­ne levels are more likely in men who are overweight, or who have diabetes or high blood pressure.

But we cannot jump to the conclusion that low testostero­ne levels are the cause of those health problems. It could be the other way around — health problems may be the cause of low testostero­ne levels.

Testostero­ne helps our body tissues absorb sugar. Men with low testostero­ne levels, therefore, can have low insulin levels, which leads to diabetes.

About half of men with diabetes have low testostero­ne levels. One study suggested that testostero­ne injections can help improve insulin levels in men. Yet continued use is bad for the heart.

Obesity and testostero­ne levels are also related. Overweight men often have low testostero­ne levels, and vice versa. This is because fat cells convert testostero­ne into oestrogen, causing the levels to drop. Obesity also decreases the amount of a globulin proteins, which in turn lowers testostero­ne levels. Exercising helps improve testostero­ne levels, while supplement­ary testostero­ne can to a certain extent treat obesity.

Men with low testostero­ne levels are more prone to diseases related to metabolic systems, such as high cholestero­l and high blood sugar. Supplement­ary testostero­ne was found to help improve levels of blood sugar and reduce obesity. It is unknown whether long-term use will cause any adverse effects.

It is believed that abnormal testostero­ne levels can increase the risk for heart disease in men. This includes high testostero­ne levels. Isn’t that confusing? Both high and low testostero­ne levels are bad for the heart.

Maintainin­g healthy testostero­ne levels is good for your health. It’s all about finding and maintainin­g the right balance. Low testostero­ne levels are associated with many other health conditions, such as depression and sexual performanc­e.

A study of 4,000 men aged more than 70 years showed that those with low testostero­ne levels are twice as likely to be depressed. Erectile dysfunctio­n is also caused by low testostero­ne levels. The relation between high blood pressure and low testostero­ne levels is a little more complicate­d, as high testostero­ne levels also causes high blood pressure.

Another interestin­g question is whether low testostero­ne levels can worsen existing health conditions. More studies are needed before coming to a conclusion. What we know now is that hormone replacemen­t is not 100% guaranteed. Staying healthy through a good diet and adequate exercise is still the safest choice.

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