In­fer­til­ity treat­ment ex­pert DR JARIYA LORWATTHANASIRIKUL of CONRADY A.R.T. CLINIC talks about her mis­sion to cre­ate a new life through the seven steps of in vitro fer­til­i­sa­tion (IVF)

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since the first “test-tube baby” was born in 1978, the world has wit­nessed rapid de­vel­op­ments in the world of ad­vanced re­pro­duc­tive tech­nol­ogy or in vitro fer­til­i­sa­tion (IVF). Mil­lions of ba­bies born through­out the past four decades are tes­ta­ment to the im­pact of IVF, which ex­tends far be­yond so­lu­tions to fer­til­ity prob­lems.

Although IVF gives many cou­ples high hope and suc­cess, there is never a 100 per­cent guar­an­tee that the re­pro­duc­tive tech­nol­ogy will re­sult in a suc­cess­ful preg­nancy. Dr Jariya Lorwatthanasirikul, a gy­nae­col­o­gist with ex­per­tise in the field of in­fer­til­ity treat­ments at Conrady A.R.T. Clinic, ex­plains the var­i­ous steps of re­pro­duc­tive tech­nol­ogy, so that cou­ples will bet­ter un­der­stand IVF and the re­lated pro­cesses be­fore mak­ing a life-chang­ing de­ci­sion. “IVF is one of sev­eral in­fer­til­ity treat­ment meth­ods that re­quires ad­vanced med­i­cal tech­nol­ogy and in­no­va­tion. Its com­pli­ca­tions and the high cost of treat­ment should be taken into ac­count. The suc­cess rate also varies, de­pend­ing on each cou­ple. Hence, we’d like to pro­vide in­for­ma­tion about the ob­jec­tive and the seven steps of IVF treat­ment in or­der to un­der­stand the ben­e­fits and to op­ti­mise the suc­cess rate,” Dr Jariya says.

Step One: Coun­selling

This step is aimed at check­ing the phys­i­cal con­di­tions and each cou­ple’s need for iden­ti­fy­ing a suit­able treat­ment method. Some cou­ples may have to change their life­styles in or­der to pre­pare eggs and sperms, while oth­ers can start the process right away. The cost of treat­ment, the op­por­tu­nity for preg­nancy and other re­lated com­pli­ca­tions will also be ex­plained at this step.

Step Two: Stim­u­lat­ing Egg Growth

An in­jec­tion pro­gramme will be planned. Blood tests will also be con­ducted to fol­low up on the egg growth and to mea­sure hor­mone lev­els. An ul­tra­sound will be per­formed. As the egg grows, in­jec­tions will also be con­ducted to stim­u­late ovu­la­tion for egg col­lec­tion.

Step Three: Egg Col­lec­tion

A nee­dle will be used for col­lect­ing liq­uid in­side the egg for a lab test. Dr Jariya fur­ther ex­plains that a light anaes­thetic will be given for a deep sleep ef­fect. An anes­the­si­ol­o­gist will closely mon­i­tor the process, which usu­ally takes around 10-15 min­utes.

Step Four: Lab Fertli­sa­tion

A sci­en­tist will take care of the egg fer­til­i­sa­tion process in a lab. The male part­ner will be asked to pro­vide a sam­ple of his se­men close to the time of egg col­lec­tion. Con­tained within this sam­ple are the sperm to be used for

fer­til­i­sa­tion, which are then pre­pared. A small con­cen­tra­tion of sperm will be placed onto each egg for nat­u­ral fer­til­i­sa­tion, or by the In­tra­cy­to­plas­mic Sperm In­jec­tion (ICSI), the tech­nique of in­ject­ing a sperm di­rectly into an egg to pro­mote fer­til­i­sa­tion. The em­bryo will be pro­duced and raised in a con­tainer for growth mon­i­tor­ing.

Step Five: Rais­ing the Em­bryo

The sci­en­tist will raise the em­bryo un­til it reaches the blas­to­cyst stage, usu­ally about six days. The em­bryo is then ready to be trans­ferred to the uterus.

Step Six: Al­ter­na­tives for Cou­ples

A com­pre­hen­sive chro­mo­some screen­ing may be un­der­taken as an op­tion for cou­ples to iden­tify ab­nor­mal­i­ties such as Down Syn­drome and tha­las­saemia. Each cou­ple can se­lect screen­ing tests they may need in this step.

Step Seven: Em­bryo Trans­fer

This is the process that the en­dometrium, the layer in which the im­plan­ta­tion takes place in the uterus, will be pre­pared for em­bryo trans­fer. Around eight days af­ter the em­bryo was trans­ferred to the uterus, hor­mone check­ing will be car­ried out to en­sure that the IVF process and the preg­nancy are suc­cess­ful.

Apart from these seven steps of IVF, Dr Jariya also em­pha­sizes, “At Conrady A.R.T. Clinic, we’re ready to sup­port a cou­ple’s ef­fort to meet the chal­lenges by us­ing our ap­proach of pa­tient-cen­tric care. The cou­ples will be able to par­tic­i­pate in ev­ery step of the fer­til­ity treat­ment to un­der­stand the dif­fi­cul­ties and op­tions they have for mak­ing a de­ci­sion. Our ser­vice en­ables cou­ples to choose the most suit­able op­tion for their needs, for a bet­ter re­sult and a preg­nancy suc­cess.” Tel. +66 (02) 494 8320 Email: ser­[email protected] Web­site:

“At Conrady A.R.T. Clinic, we’re ready to sup­port a cou­ple’s ef­fort to meet the chal­lenges by us­ing our ap­proach of pa­tient-cen­tric care”

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