Daily Sabah (Turkey)

Professor develops treatment against COVID-19

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PROFESSOR Derya Unutmaz, a Turkish researcher from the Jackson Laboratory in the United States, announced that he and his team have achieved progress in a new treatment method effective against all variants of the coronaviru­s.

Speaking to Anadolu Agency (AA) yesterday, Unutmaz said the method is based on synthetic biology technology. “COVID-19 variants can escape antibodies the body develops and thus, even fully vaccinated people can be infected. The omicron variant showed us this fact,” he said.

“We were working on an immunity system countering all variants and succeeded,” he added. The treatment method developed by Unutmaz and his team of researcher­s works to “trap” the virus. “The surface of the virus hosts spike protein that enables it to merge itself with cells and spread. Then, it generates its own proteins in the body and replicates them to spread to other cells. This was much more advanced in omicron. Our method involves the conversion of cells (protection mechanism) into a molecule, which helps neutralize the virus and prevents it from spreading all across the cell,” Unutmaz said. He said that the method would be efficient against any future variants as well.

“It works like a laser tag on infected cells for T-cells in the immunity system, helping them to target the correct infected cells,” he elaborated.

The study began about one year ago, and the team has succeeded in developing it in a lab environmen­t. They now plan to start animal and, subsequent­ly, human trials. Unutmaz said they plan to wrap up the animal trials by this summer and expect to achieve results in human trials by the end of the year.

He noted that the method was a “first” against the coronaviru­s and was inspired by immunother­apy treatments against cancer, which his team had been working on for some time.

“It has been almost two years with the pandemic. It has been difficult, but people should not fall into despair. I believe that, with omicron, the pandemic will largely cease. With the methods we developed, we will ready our defense against future variants. Humanity and science will triumph,” he added.

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