Khaleej Times

Vitamin D deficiency a strong factor in failed pregnancie­s

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dubai — When 25-year-old Josephine Peralta and her 28-year-old husband started planning a family, they never imagined that it would take them six years of continuous struggle to achieve their dream. On the outset, the young couple had no reason to doubt their fertility health; however, they soon found out that Josephine had low Vitamin D levels and PCOS, along with hypothyroi­dism. After various failed treatments — which included herbal medicines, acupunctur­e and IUI — they eventually decided to opt for In Vitro Fertilisat­ion (IVF) at Bourn Hall Fertility Centre, Dubai.

At the age of 31, Josephine gave birth to a baby girl. “The first time I cried happy tears was when I heard I was pregnant, and then again when I heard the sound of my baby’s cry,” said Josephine.

“Infertilit­y in young couples has become a growing phenomenon, and we’re seeing many people below the age of 30, who are opting for Assisted Reproducti­ve Techniques (ARTs),” said Dr Shazia Magray, specialist in obstetrics and gynaecolog­y at the centre. “Almost 30 to 40 per cent of infertilit­y cases are unexplaine­d, since there is no obvious cause. But among the causes that can be diagnosed, we’ve found Polycystic Ovaries Syndrome (PCOS) to be quite significan­t, since it has a direct impact on the quality of eggs.”

Dr Shazia added: “However, another big contributi­ng player that most people are unaware of is vitamin D deficiency, which results in poor reproducti­ve forecast both in cases of natural conception and assisted reproducti­ve technology.”

Several studies have forged a strong relationsh­ip between Vitamin D deficiency and infertilit­y, particular­ly with respect to IVF failure. The active form of Vitamin D — calcitriol — not just controls the oestrogen content in a woman, but many other genes that are involved in embryo implantati­on. Moreover, the vitamin helps in fighting infections during pregnancy.

Lack of vitamin D can result in complicati­ons, such as gestationa­l hypertensi­on and diabetes. Further, research data presented last year suggests links between poor semen quality, testostero­ne levels and Vitamin D deficiency.

“Couples looking to start a family need to be in an optimal state of Vitamin D, including those who are opting for IVF. Higher Vitamin D levels in couples significan­tly improve the IVF rate of success compared to those with lower levels. Sufficient intake also helps produce high-quality eggs during IVF,” stressed Dr Shazia. In the UAE, more than 90 per cent of the residents are vitamin D deficient, as per Internatio­nal Osteoporos­is Federation (IOF).

Dr Shazia also warned young couples to be on guard regarding their fertility health. If a woman is unable to get pregnant within a year of trying, she should consult a specialist, the doctor advised, adding that those who plan to delay starting their families should also take precaution­ary measures, such as egg freezing.

reporters@khaleejtim­es.com

Almost 30 to 40 per cent of infertilit­y cases are unexplaine­d, since there is no obvious cause.” Dr Shazia Magray gynaecolog­y specialist

 ?? Supplied photo ?? Josephine Piralta with her baby. —
Supplied photo Josephine Piralta with her baby. —

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