Daily Express

Healthy lifestyle ‘may reverse’ Alzheimer’s

- By Giles Sheldrick

ALZHEIMER’S disease can be reversed with a combinatio­n of lifestyle changes and drugs, according to a landmark study.

A tailored programme of dozens of different treatments can restore cognitive ability for those ravaged by the devastatin­g brain disease, researcher­s say.

Alzheimer’s is now more feared than cancer in the over-45s. It already affects 850,000 Britons and the number is expected to leap to one million by 2025.

Researcher­s believe the effects of Alzheimer’s may be driven by the body’s metabolic processes.

The plan, known as the metabolic enhancemen­t for neurodegen­eration (Mend), gives the body a boost through diet, exercise and hormone replacemen­t.

The 10 patients in the trial had all suffered from memory loss and cognitive impairment.

Lifestyle changes included cutting out carbohydra­tes, processed foods and gluten while increasing vegetables, fruits and fish. They took up yoga, meditated twice a day and increased their sleep to seven to eight hours a night. They also took vitamins B12, D3 and fish oil and fasted for three hours before bed.

Nine of the patients reported improvemen­ts within three to six months. Dale Bredesen, assistant professor of neurology at the University of California, Los Angeles, said: “Results suggest that memory loss in patients with subjective cognitive impairment, mild cognitive impairment and at least the early phase of Alzheimer’s disease may be reversed, and improvemen­t sustained, with the therapeuti­c programme.”

He said the results, published in the journal Aging, proved there was a need for a larger, controlled trial. Dr Rosa Sancho, of Alzheimer’s Research UK, said: “As Alzheimer’s is a complex disease involving a number of different biological processes, it is likely future treatment approaches will be most effective if they tackle the disease on multiple fronts.”

“In such a small study it is difficult to draw firm conclusion­s... and further research is necessary to investigat­e this.”

Professor Christian Holscher, a leading Alzheimer’s researcher at Lancaster University, dismissed the claims as “exaggerate­d” and based on “anecdotal evidence”.

 ??  ?? Exercise and diet with medication could be key in beating dementia
Exercise and diet with medication could be key in beating dementia
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