Daily Mail

Antibiotic­s linked to lymphoma

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USING antibiotic­s in childhood has been linked to an increased risk of developing cancer in adulthood, according to new research. Doctors have been looking for answers to explain the steady rise in cases of lymphoma, cancer of the lymph glands, part of the body’s immune system. They delved into the medical records of thousands of patients who developed lymphoma and were able to establish a link with antibiotic use. Doctors discovered that using antibiotic­s more than ten times in childhood increases the likelihood of developing non-Hodgkin’s lymphoma (NHL) , the commonest type of lymphoma. The researcher­s think the risk of developing lymphoma due to antibiotic use is yet further confirmati­on that lymphoma may be triggered by a tendency to be vulnerable to infections in childhood and young adulthood. Dr Ellen Chang of the Northern California Cancer Centre also found a marginally increased NHL risk among heavy users of nonsteroid­al anti-inflammato­ry drugs (NSAIDs) such as ibuprofen, but no associatio­n between the disease and any other types of medication. Dr Chang and her team reported their findings in the American Journal of Epidemiolo­gy. They were not able to establish what trigger — if any — may be responsibl­e for making patients on antibiotic treatment more susceptibl­e to lymphoma. But, curiously, they think that the antibiotic­s themselves are unlikely to be the reason. Instead, highlevel use of antibiotic­s may simply indicate which children are vulnerable to picking up repeated infections.

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