Daily Mail

Steam clean your lungs back to life

- By ROGER DOBSON

ABLAST of steam that scalds the l ungs may provide relief to patients with breathing disorders such as emphysema. New research s hows t hat t he 30- minute procedure can i mprove l ung function and reduce breathless­ness — as a result patients are also able to exercise more easily.

Up to two million Britons suffer from breathing disorders such as emphysema — these disorders fall under the umbrella term chronic obstructiv­e pulmonary disease (COPD).

Healthy lungs contain hundreds of millions of tiny air sacs called alveoli, which help in the absorption of oxygen into the blood as well as removing carbon dioxide.

In emphysema patients, these tiny air sacs become inflamed, and in many cases are damaged and destroyed, triggering coughing and breathless­ness.

This is frequently due to the effects of smoking, but the condition can also affect non-smokers — either through a genetic susceptibi­lity, or exposure to workplace chemicals.

In more severe cases, surgery is used to remove the worst affected parts, cutting the size of the lungs.

This reduces the strain on the organ because the air is inhaled into a smaller space, making breathing easier. However, many people with the disease are not generally well enough to undergo such extensive surgery, and hospital stays can last up to two weeks.

THE new therapy, developed by U.s.-based Uptake Medical, also reduces the volume of the l ungs, but uses steam, rather than surgery, in a procedure that requires just an overnight stay in hospital.

First the lungs are scanned to identify the dysfunctio­nal areas. An endoscope or tube is then inserted into the lungs through the airway.

A small balloon is fed down this tube and inflated in the l ungs to block off the area being treated, so that steam does not flow backwards into healthy parts of the lung. Then steam is fired through the tube into the targeted lung tissue, scalding t he t i ssue. Each vapour blast l asts between three and ten seconds.

Over the following weeks, scar tissue forms which shrinks the tissue — in the same way that a scar pulls the skin around a wound tight. This reduces the volume of the lungs, making breathing easier. Results from internatio­nal trials of more than 50 patients show the therapy leads to significan­t improvemen­ts in lung function (measured as a reduction in breathless­ness), and increases the amount of physical activity they could perform, which was gauged by the distance they could walk in six minutes. There were also improvemen­ts in overall quality of life.

Dr Felix Herth, head of Pulmonary Medicine at the University of Heidelberg, Germany, who led one of the studies, said: ‘A procedure that shows an 83 per cent improvemen­t when looking at several end points [ such as lung capacity and level of physical activity] should provide new optimism for patients who are living with emphysema.’

The treatment has recently been approved for use in the UK and Europe and in the past few weeks has been used to treat patients in Germany. It is not currently available

in t he UK. Commenting on the research, Professor Michael Polkey, consultant physician at Royal Brompton & Harefield NHS Foundation Trust, said: ‘This latest research avoids the need for surgery, which can mean patients suffer less discomfort and recover more quickly.

‘At Royal Brompton we carried out the first UK clinical trial of lung volume reduction surgery which is now a widely-accepted therapy for selected patients and the outcomes are extremely good. We are also planning further studies using non-invasive techniques.’

DAME Helena Shovelton, chief executive of the British Lung Foundation, added: ‘Using steam is a developing area, but there is insufficie­nt evidence about the benefits at the moment. We look forward to seeing more clinical trial results.’

MEANWHILE, scientists have developed a new smoke-free electronic cigarette to help smokers quit the habit. Smoking is linked to breathing problems such as emphysema.

The device contains nicotine yet produces no smoke and none of the carbon monoxide, tar or toxins that makes smoking tobacco such a health risk.

The hand-held device consists of a rechargeab­le lithium battery that powers a vaporiser. This instantly turns a nicotine solution that is held in the device into a vapour that the user then inhales.

The manufactur­er of the device, known as Nicadex, says many users report using it produces a similar sensation to smoking.

This device i s now being submitted to clinical trials in order to be classified as a prescripti­on nicotine replacemen­t product, similar to nicotine patches.

The manufactur­er expects to apply for regulatory approval of the electronic inhaler in the UK later this year.

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