Daily Mail

Antibiotic­s ‘raise risk of obesity in toddlers’

- By Toby McDonald and Fiona MacRae

BABIES given antibiotic­s in their first six months are more likely to become fat toddlers, a large-scale study has found.

Researcher­s said the widely prescribed drugs could be contributi­ng to the obesity epidemic.

A third of those aged ten or 11 and more than a fifth of four to five-year- olds in England are overweight or obese, leading to fears they will be the first generation to die at an earlier age than their parents.

Scientists in Finland compared the weight and height of more than 12,000 healthy two-year-olds with prescripti­on records. One in five boys and one in ten girls was overweight or obese.

Children who had taken antibiotic­s as young babies were particular­ly likely to be overweight. Repeated prescripti­ons before the age of two also raised the odds of being a fat toddler.

Boys who had been given antibiotic­s seemed particular­ly prone to weight gain.

The study, in the respected medical journal Pediatrics, did not conclusive­ly prove that antibiotic­s were causing weight gain.

But if the drugs do have such an effect, it may be because they kill off bugs in the gut that would normally use up some of the food a person eats. Killing certain gut bugs may also increase appetite.

Lead author Dr Antti Saari, of Kuopio University Hospital, warned: ‘Antibiotic exposure before six months of age, or repeatedly during infancy, was associated with increased body mass in healthy children.

‘Such effects may play a role in the worldwide childhood obesity epidemic … An increase in the use of antibiotic­s could be an additional contributi­ng factor to the developmen­t of excess weight problems … their extended use today has undesirabl­e and unexpected consequenc­es.’

It comes amid growing concern over-prescripti­on is leading to antibiotic­s losing their power, making infections harder to treat.

Dr Martin Ward-Platt, of the Royal College of Paediatric­s, said the study was ‘striking’. He said recent guidance to prescribe antibiotic­s more to very young babies could unwittingl­y further increase childhood obesity rates.

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