Daily Mail

Cannabis users five times more likely to develop schizophre­nia

- By Victoria Allen Science Correspond­ent

REGULAR cannabis users are more than five times more likely to develop a serious mental disorder.

Cannabis creates a greater mental health risk than any other substance, including class A drugs, scientists have found.

Those who abuse the drug – now more potent than ever in the form of superstren­gth ‘skunk’ – are 5.2 times as likely to develop schizophre­nia.

This compares to 1.9 times for hallucinog­enic drugs and 1.24 times for amphetamin­es. Danish researcher­s trawled more than 3.1million people’s medical records to ascertain the link between cannabis use and schizophre­nia.

In research presented to the Internatio­nal Early Psychosis Associatio­n, they sug- gested the pleasure hormone dopamine, released by the drug, could trigger the disorder in people susceptibl­e to its effects.

The mass medical records study looked at people diagnosed as being cannabis abusers by doctors and those who were schizophre­nics. It follows research last year which showed super-strength types of cannabis caused one in four cases of psychosis.

More than nine million people in England and Wales have smoked cannabis at some point. Pro-cannabis campaigner­s say the drug cannot be proven to have caused the psychotic disorder. They claim people may be schizophre­nics before they use cannabis and are more likely to take the drug in the early stages of illness to calm themselves.

But the researcher­s at Copenhagen University Hospital’s Mental Health Centre also found evidence implying that cannabis made the brain schizophre­nic. In a second study they discoverin­g that pregnant women who abused cannabis gave birth to children six times more likely to become schizophre­nics. This suggests the physical effects of the drug could be passed on in the womb.

Study leader Dr Carsten Hjorthøj, said: ‘We know a child in its mother’s womb is not doing this by choice, is not medicating itself. For me, that does set upon the idea that cannabis is a causal mechanism.

‘We know schizophre­nia is a disorder of the brain linked to dopamine and cannabis influences levels of dopamine.’

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