Daily Mail

Pollution ‘sparks 10 per cent rise in cancer cases’

- By Victoria Allen Science Correspond­ent

AIR pollution contribute­s to a 10 per cent rise in people being diagnosed with cancer, a study has found.

US researcher­s believe it causes an extra 44 cases per 100,000 people – equivalent to more than 28,600 cancer diagnoses in Britain.

The study, published in the journal Cancer, is the first to examine the link between environmen­t and cancer, although previous research has found diesel fumes could cause women to give birth prematurel­y.

Its authors say developing the disease is 50 per cent due to genetics, but environmen­t also damages our DNA, changes the way genes work and can even alter important hormones.

They examined the population­s of almost 2,700 counties across America, where cancer affected an average of 451 people in every 100,000 between 2006 and 2010.

The extra 44 cases found in the worst polluted counties compared to the cleanest represents a rise of around 10 per cent, while socioecono­mic circumstan­ces and roads also increased risk.

Lead author Dr Jyotsna Jagai, from the University of Illinois, said: ‘Our study is the first we are aware of to address the impact of cumulative environmen­tal exposures on cancer incidence.

‘This work helps support the idea that all of the exposures we experience affect our health, and underscore­s the potential for social and environmen­tal improvemen­ts to positively impact health outcomes.’

Lung cancer had already been linked to diesel exhausts and polycyclic aromatic hydrocarbo­ns, produced by cars and also thought to cause asthma and heart dis- ease. But an extra ten cases of prostate cancer per 100,000 men were also attributed to air pollution, with almost four extra cases of breast cancer per 100,000 women. The reasons behind this increase are still being examined, but the study states: ‘Environmen­tal exposures can alter or interfere with a variety of biological processes, including hormone production and function, inflammati­on, DNA damage and gene suppressio­n or over-expression.’

Previous research has suggested particles of pollution can mimic oestrogen, which is known to fuel breast cancer.

They can also make women’s breasts denser, which raises their danger of the cancer.

To investigat­e the effects of overall environmen­tal quality, the researcher­s looked at air, water and land quality, as well as the built environmen­t and social factors. When adjusting for age, the annual incidence was 451 cancer cases per 100,000 people.

But counties with poor environmen­tal quality had on average 39 more cases per 100,000 people than those of high quality.

Water quality had little or no effect on cancer rates when taken in isolation, with land quality, including the use of pesticides, having a small effect.

Air quality alone was found to cause an extra 44.19 cases per 100,000 over the four years.

Dr Jagai said: ‘Therefore, we must consider the overall environmen­t that one is exposed to in order to understand the potential risk for cancer developmen­t.’

Toxic nitrogen oxide fumes, which come mainly from diesel cars, are linked to the deaths of 23,500 people in Britain every year. Scientists led by the University of York concluded earlier this year that air pollution may be helping to cause up to 4,500 premature births a year in Britain.

‘Environmen­t can alter processes’

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