Daily Mail

Tossing and turning could be early sign of Parkinson’s

- By Ben Spencer Medical Correspond­ent b.spencer@dailymail.co.uk

THRASHING about in your sleep could mean you have a higher risk of developing dementia or Parkinson’s disease, experts say.

Kicking and punching at night is characteri­stic of a condition called REM sleep behaviour disorder.

Academics say 80 per cent of those who have a severe case of this eventually develop a neurologic­al disease.

The restless behaviour may predict dementia and other diseases up to 15 years before symptoms appear.

Those with sleep behaviour disorders often toss and turn at night, meaning they feel bleary-eyed and fall asleep in the daytime.

In some cases their movements are so vigorous that they can hurt themselves or their partners.

Dr John Peever, of the University of Toronto, who presented his research at the Canadian Associatio­n for Neuroscien­ce annual conference yesterday, thinks sleep disorders are caused by dysfunctio­nal brain stem cells.

When most people dream, if these cells are fully functionin­g, the body is ‘paralysed’ so we do not act out the scenes being played in the mind.

The cells – called REM-active neurons – switch on when the body enters a state of deep sleep known as REM or rapid eye movement sleep, when the eyes dart around beneath the eyelids. This is when we tend to experience vivid dreams.

But for those with sleep disorders these cells never switch on, meaning the body moves around when we dream.

Dr Peever thinks these dysfunctio­nal cells also play a role in Parkinson’s, dementia, and other brain and nervous system problems in the elderly. He said: ‘ When we switch on these cells, it causes a rapid transition into REM sleep.

‘Our research suggests sleep disorders may be an early warning sign for diseases that may appear some 15 years later in life.’ Dr Peever hopes his research will eventually allow doctors to predict which patients are likely to develop the diseases.

Knowing someone is at risk may help them adopt a healthier lifestyle, which could delay onset of the illnesses.

Dr Peever added: ‘Much like we see in people prone to cancer, diagnosing REM disorders may allow us to provide individual­s with preventati­ve actions to keep them healthy long before they develop these more serious neurologic­al conditions.

‘ This goal will take years to develop yet, but could one day help thousands of peo- ple live healthier lives long before they need serious medical attention.’

Teenagers who use mobile phones at night are more likely to suffer poor sleep and be depressed, a study has found.

Parents should consider ‘digital curfews’ in the evening, according to the Australian researcher­s from Murdoch and Griffith universiti­es.

The three-year study of 1,101 teenagers, published in the journal Child Developmen­t, also found that those who used phones after nightfall tended to have lower self-esteem and be more aggressive.

‘Often fall asleep during daytime’

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