Daily Mail

MRI ‘spots 46% more cases of prostate cancer’

- By Ben Spencer Medical Correspond­ent

END THE NEEDLESS PROSTATE DEATHS

THOUSANDS of cases of aggressive prostate cancer could be spotted early by using cuttingedg­e MRI scans, a major study has found.

An internatio­nal team led by University College London found they could diagnose 46 per cent more aggressive tumours by using MRI scans rather than relying on biopsies.

The NHS-funded study, presented at the European Associatio­n of Urology congress in Copenhagen yesterday, also found the number of men subjected to painful biopsies was cut by more than a quarter.

If the approach was rolled out across the health service, it would mean 28,000 British men each year could be spared the invasive probes.

The NHS is already piloting the use of MRI in several ‘onestop’ services, as revealed by the Daily Mail this month. But the new findings – the largest study conducted into the use of the scans – provides the most compelling evidence yet that they can make a major difference to patients’ outcomes.

The Mail is campaignin­g for an urgent improvemen­t of prostate cancer treatments and diagnosis, which are lagging years behind other diseases such as breast cancer.

Currently any man thought at risk of prostate cancer is subjected to a biopsy – a small tissue sample removed from their prostate. Some 100,000 middleaged British men undergo this procedure each year, usually after a blood test has picked up raised levels of ‘prostatesp­ecific antigen’, known as PSA. But biopsies are notoriousl­y painful and come with a risk of side effects including infections and bleeding.

The new study, involving 23 hospitals in 11 countries, instead used MRI scans to give doctors a detailed picture of the prostate. The researcher­s were able to give the all-clear to 28 per cent of men, meaning they did not need a biopsy.

For the remainder, doctors were able to conduct the biopsy with far greater accuracy, using the MRI scan to sample directly from suspicious tissue.

They found they diagnosed 46 per cent more ‘clinically significan­t’ cancers this way – 38 for every 100 men scanned, compared to 26 for every 100 men who underwent a biopsy alone.

They also slashed by 59 per cent the number of ‘insignific­ant’ cancers diagnosed – those that would never cause a problem – from 22 per 100 using biopsies to nine per 100 for those using MRI.

Karen Stalbow of Prostate Cancer UK said: ‘For too long men have had to endure a stabin-the- dark biopsy technique, which can miss one in four harmful prostate cancers. It is now more important than ever that all men with suspected prostate cancer get a multi-parametric MRI scan before biopsy.’

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