Daily Mail

Mr Right may be the wrong choice to start a family

Women’s eggs may ‘pick’ another man

- By Victoria Allen Science Correspond­ent

WOMEN can spend ages finding the perfect man before starting a family.

However, when it comes to biology, Mr right could actually be wrong.

While a woman may want her partner to father her children, a study has found that her eggs might have other ideas.

researcher­s recruited 60 couples having IVF to see how compatible they were.

Women’s eggs release chemicals that appear to signal to sperm, encouragin­g them to swim over to make a baby. But for some women, the chemicals worked better for sperm from a man who wasn’t their partner.

experts believe women’s bodies can somehow ‘choose’ sperm, making sure it is high quality and geneticall­y compatible.

Professor Daniel Brison, senior author of the study at Saint Mary’s Hospital, part of Manchester University NHS Foundation Trust, said: ‘We expected that a particular woman’s eggs would attract the sperm of her partner, but did not see this.

‘In fact, overall, women’s eggs attracted other men’s sperm as often as their partners’ sperm.

‘We hope it will advance fertility treatment and may help to understand some of the “unexplaine­d” infertilit­y in couples. There might even be a treatment to help eggs attract a partner’s sperm better.’

Compared with other animals, humans aren’t very good at making babies. Just 250 individual sperm make it to a woman’s fallopian tube after sex, and only around 25 are capable of fertilisin­g an egg to get her pregnant.

The study suggests the eggs help by producing chemicals in the fluid surroundin­g them. researcher­s took this fluid from 60 women, and sperm samples from their partners.

The sperm were given an hour to swim more than 1in to the fluid. It emerged that they travelled in greater numbers towards chemicals released by women’s eggs than a laboratory version, showing that eggs may be able to ‘summon’ sperm.

But researcher­s also swapped sperm and egg fluid between two sets of couples. This showed women’s eggs often produced chemicals better able to attract a stranger’s sperm than their partner’s. a couple was no more compatible than with people from another couple on average.

If a woman’s eggs did lure her partner’s sperm, the couple had better IVF results on average.

But the authors, whose research is published in the journal Proceeding­s of the royal Society B, say this result was only strongly seen in one couple, and egg and sperm compatibil­ity did not affect the chance of becoming pregnant by IVF.

Co-author John Fitzpatric­k, of Stockholm University, said: ‘Interactio­ns between human eggs and sperm depend on the identity of the women and men.’

‘Unexplaine­d infertilit­y’

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