Daily Record

Well, hello Dolly!

- BBC2, 9pm

TWENTY-FIVE years on, this is the revolution­ary story of the men and women who created the sheep that changed the world forever – Dolly.

Told by the scientists who created her, it takes us through how Dolly was made, using controvers­ial research and techniques previously thought impossible. It combines unpreceden­ted access and archive footage to tell the human story behind the sheep that became the rock star of science.

It all began in the early 90s, on a small Scottish sheep farm, where a handful of the world’s best genetic scientists had been working in secret for over a decade, to crack cloning.

Roslin Institute is now one of the top research labs in the world, but back in 1997 it was largely unknown.

However, it did have a rising star in animal breeding, Ian Wilmut. He worked alongside Keith Campbell, a specialist in cell technology who had a crazy theory that could bring Dolly to life.

When Margaret Thatcher came to power, research centres like this were asked to prove their economic worth, so, having just made the cut, they decided to explore genetic engineerin­g.

In the 80s, scientists had taken a growth gene from a rat and injected it into a mouse egg. The result? Giant mice.

Dr Alan Colman, Roslin research director and molecular biologist at the time, says: “What would happen if we manipulate­d human eggs? Everyone could be a great basketball player. People said ‘You’re playing God’.”

But being able to pinpoint specific genetic mutations raised the possibilit­y of fighting disease, and the institute decided to get on board.

 ?? ?? GAME-CHANGER Professor Sir Ian Wilmut and historic sheep Dolly
PICK of the DAY
GAME-CHANGER Professor Sir Ian Wilmut and historic sheep Dolly PICK of the DAY

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