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BRIGHTON will hand a late fitness test to forward Jose Izquierdo, who has been struggling with a knee injury. Glenn Murray should be available following a shoulder injury, but Shane Duffy is suspended. CHELSEA striker Alvaro Morata (knee) is a doubt, as are Mateo Kovacic, Gary Cahill and Victor Moses. Kepa Arrizabalaga, Antonio Rudiger, Eden Hazard, Cesar Azpilicueta and N’Golo Kante should return after being rested for Thursday’s Europa League tie with Hungary’s Vidi.

Last season: Brighton 0 Chelsea 4.

Top scorers: Glenn Murray (Brighton) 8; Eden Hazard (Chelsea) 7.

Referee: Stuart Attwell.

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LIVERPOOL boss Jurgen Klopp has defence issues, as right-back Trent Alexander-Arnold (foot) and Joel Matip (broken collarbone) this week joined Joe Gomez (fractured leg) on the injury list. Midfielder James Milner is likely to start at right-back. MARCOS ROJO is set to miss out for United, as are Victor Lindelof and Alexis Sanchez. Chris Smalling, Diogo Dalot, Anthony Martial, Matteo Darmian, Luke Shaw and Scott McTominay are doubts.

Last season: Liverpool 0 Man Utd 0.

Top scorers: Mo Salah (Liverpool) 10; Anthony Martial (Man Utd) 7.

Referee: Martin Atkinson.

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SOUTHAMPTON will be without injured defenders Ryan Bertrand (back) and Jack Stephens (knee). They are boosted by the return of strikers Danny Ings (hamstring) and Shane Long (ankle), as well as rightback Cedric Soares (calf). LAURENT KOSCIELNY is Arsenal’s only available recognised centre-back – having just returned from an Achilles problem. Sokratis Papastathopoulos and Shkodran Mustafi are banned, while Rob Holding (knee) and Konstantinos Mavropanos (groin) are injured.

Last season: Southampton 1 Arsenal 1.

Top scorers: Danny Ings (Southampton) 4; Pierre-Emerick Aubameyang (Arsenal) 10.

Referee: Chris Kavanagh.