BBC Science Focus

ARE ANTIBIOTIC­S MAKING US FAT?

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The past five years have seen interest in the idea that our gut bacteria play a crucial role in regulating weight, and killing them off with antibiotic­s is causing obesity.

The most recent evidence is fascinatin­g but inconclusi­ve. Studies in prestigiou­s medical journals have produced contrastin­g results. One found that three courses of antibiotic­s before the age of two was associated with increased risk of early childhood obesity, while the other found that exposure to antibiotic­s in the first six months of life was not associated with early childhood weight gain.

Yet recent research is indicating a link between gut fauna and our body mass index. People with higher levels of Christense­nellaceae bacteria – one in 10 of us – appear less likely to put on weight than those with lower amounts. Scientists from King’s College London have found that levels of this bacteria are partly geneticall­y determined.

According to Yeo, who investigat­ed the possibilit­y of microbial transplant­s to cure obesity for a BBC programme, this new field is important and requires research. “But I have yet to see convincing evidence that there are lean bacteria and obese bacteria,” he says.

Verdict: More research needs to be done, but our gut bacteria may affect how readily we put on weight.

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