BBC Science Focus

OCTOPUSES HIGH ON MDMA BECOME TOUCHY-FEELY

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If ASBOs were given out to sea creatures, it’s highly likely octopuses would get slapped with more than their fair share. They spend much of their lives alone, frequently get into fights and have even been known to attack and kill one another after mating. Now, a study at Johns Hopkins University has found that giving them a small dose of MDMA – a psychoacti­ve drug also known as ecstasy – makes them so sociable that they touch and hug one another.

The findings suggest there could be an evolutiona­ry link between the social behaviours of the sea creatures and humans despite the species being separated by 500 million years on the evolutiona­ry tree, the researcher­s say.

“The brains of octopuses are more similar to those of snails than humans, but our studies add to evidence that they can exhibit some of the same behaviours that we can,” said assistant professor Gül Dölen, at Johns Hopkins University School of Medicine. “What our studies suggest is that certain brain chemicals, or neurotrans­mitters, that send signals between neurons required for these social behaviours are evolutiona­rily conserved.”

The team placed four California two-spot octopuses that had been exposed to MDMA, one at a time, into a set-up of three connected water chambers: one empty, one with a plastic action figure under a cage and one with a female or male laboratory-bred octopus under a cage. All four tended to spend more time in the chamber where the octopus was caged. Under normal conditions, without MDMA, the octopuses avoided the male caged octopuses.

“It’s not just quantitati­vely more time, but qualitativ­e. The octopuses tended to hug the cage and also put their mouth parts on the cage,” said Dölen. “This is very similar to how humans react to MDMA; they touch each other frequently.”

However, the team at Johns Hopkins University School of Medicine cautions that the results are preliminar­y and need to be replicated before octopuses might be used as models for brain research.

 ??  ?? The drug ecstasy appears to have a similar effect on octopuses’ brains as it does on humans’
The drug ecstasy appears to have a similar effect on octopuses’ brains as it does on humans’

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