Scottish Daily Mail

Patients are STILL not being warned of withdrawal pain from depression pills, say experts

- By JONATHAN GORNALL

Patients are still not being warned how difficult it can be to come off antidepres­sants, say psychiatri­sts campaignin­g for a reduction in the needless use of the drugs.

Yet the withdrawal symptoms are frequently mistaken for a relapse in the condition for which the drugs were prescribed and, as a result, patients end up being put back on them. the psychiatri­sts are now calling for prescribin­g guidelines to be updated urgently.

Under present UK-wide niCe guidance, unchanged since 2004, withdrawal symptoms are described as ‘usually mild and self-limiting over about one week’. But research and patients suggest otherwise, with severe symptoms including nausea, insomnia, anxiety and panic attacks that can last weeks – or longer.

Last October, Mail research confirmed the frequency, severity and duration of reactions to antidepres­sant withdrawal was ‘more widespread, severe and longlastin­g’ than doctors had been led to believe, with nearly half of patients suffering severe symptoms (that’s 1.8 million in Britain).

now, in a letter published today in the BMJ, 14 of the world’s leading experts on antidepres­sant withdrawal are calling on niCe and the Royal College of Psychiatri­sts to review their guidelines urgently ‘to bring them in line with the scientific evidence base’.

they say it is ‘concerning’ that, despite overwhelmi­ng evidence that millions of patients battle to come off antidepres­sants for months or even years, two recent surveys show only a tiny proportion

recall being told anything about withdrawal effects, dependence or potential difficulti­es coming off the drugs.

‘the guidelines are misleading doctors about the extent to which withdrawal is an issue and this is causing devastatin­g problems for many people,’ says Dr James Davies, a reader in medical anthropolo­gy and mental health at the University of Roehampton, and one of the letter signatorie­s.

a review by Dr Davies, published last year in the journal addictive Behaviors, looked at 14 studies and found half of patients experience withdrawal when trying to stop or reduce their antidepres­sants; nearly half described their withdrawal as severe.

Dr Davies says the faulty guidance explains why, although the number of people being prescribed the drugs for the first time is slowly falling, millions are being kept on them for years.

He adds: ‘so what happens to a person who turns up at their GP surgery four weeks after stopping a drug, still experienci­ng withdrawal effects?

‘We fear those symptoms will be misdiagnos­ed as a return of their condition, and that doctors simply put them back on the antidepres­sants, leading to long-term use.’

the letter’s signatorie­s cite evidence of the physical and emotional consequenc­es of long-term antidepres­sant use, which range from weight gain to increased risk of dementia and even death.

NiCe is reviewing its guidelines on the diagnosis and management of depression. it is also developing guidelines on the ‘safe prescribin­g and withdrawal management of prescribed drugs’.

almost one in five scots were prescribed antidepres­sants last year, a total of 902,168 people.

in a petition to the scottish parliament, campaigner­s have urged the scottish Government to take action to ‘recognise and support’ people who have become dependent on and are withdrawin­g from prescripti­on drugs.

Psychother­apist Marion Brown, who brought the petition on behalf of patient group Recovery and Renewal, said: ‘there seems to be enormous resistance to any criticism of antidepres­sants – although it is becoming ever more urgent this is fully investigat­ed, as the evidence is becoming a tsunami of terrible suffering being experience­d by patients, disbelieve­d by the medical profession.’

a scottish Government spokesman said: ‘the chief medical officer for scotland is convening a working group of experts to examine prescribin­g trends, including antidepres­sants.’

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