The Critic

Blinded by science

Alasdair Palmer says there is little evidence to show that lockdowns are effective

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Alasdair Palmer says there is little evidence lockdowns are effective

Almost everyone is now thoroughly fed up with the closure of schools and all but essential businesses, and of being told that they are not allowed to venture out of their home unless it is to do food shopping or take exercise. The measures collective­ly known as the lockdown — the second imposition of the restrictio­ns in the UK in less than a year — is starting to pall. The lockdown’s sharply negative effects on Britain’s economy, on its education, and on mental health, are becoming more obvious. Most people neverthele­ss accept the lockdown is necessary, because they accept that, prior to vaccinatin­g 70 per cent of the population, it is the only effective way to restrict the spread of Covid-19.

That is what ministers emphasise at every opportunit­y. It is also what the Chief Medical Officer, Professor Chris Whitty, and the Chief Scientific Officer, Sir Patrick Vallance, say. So do many other scientists who are expert in infection and disease transmissi­on. Some go further than merely stressing the effectiven­ess of lockdowns in combatting the virus: they say that anyone who breaks the lockdown rules is a menace to public health, and is recklessly causing the spread of a deadly disease: rule-breakers have “blood on their hands”, and deserve public shaming as well as serious punishment.

And yet, the empirical evidence on the effectiven­ess of lockdowns in diminishin­g the infection and death rate of Covid-19 is surprising­ly thin. There is very little data that supports the claim that, at least until most people have been vaccinated, lockdowns are the only effective way of containing the spread of infection.

Of the many hundreds of scholarly articles published in scientific journals on the Covid virus since January last year, amazingly few even attempt to provide and analyse empirical data which shows that lockdowns are the most effective way of dealing with the virus.

The most famous article which did attempt to do so was published in the journal Nature on 8 June 2020 by a team of scientists from Imperial College London. Entitled Estimating the effects of non-pharmaceut­ical interventi­ons on Covid-19 in Europe, it claimed that not only were lockdowns effective, but they were the only effective way (other than a vaccine) of controllin­g the rate at which Covid spread and killed. The authors concluded that imposing lockdowns in the 11 European countries they studied had saved three million lives.

That figure of three million lives saved has been frequently cited since. If it, and the reasoning behind it, are accurate, that would certainly provide very powerful evidence that lockdowns are essential for coping effectivel­y with Covid. But both the conclusion and the reasoning that led to it are very seriously flawed.

The assumption­s built into the model determined

its conclusion­s. And one of the assumption­s was that lockdowns were responsibl­e for the drop in the number of Covid deaths that all the countries in the study saw in the spring and early summer of 2020. Sweden was one of the countries in the study. It was included partly because of the quality of its record-keeping.

But Sweden did not impose the measures that are required for a lockdown: there was no stay-at-home order, and businesses including bars and restaurant­s stayed open, as did schools. Neverthele­ss, in the spring and early summer, Sweden, like all the other countries in the study, experience­d a sharp fall in Covid infections and deaths.

You might think this fact would have persuaded the authors of the paper that perhaps locking down was not responsibl­e for the fall in Covid cases — or at least to have caused an agonised reappraisa­l of the model’s assumption­s. But no. It merely meant that the authors of the paper stipulated that according to the model, Sweden’s ban on gatherings of more than 100 people counted as a lockdown — which of course it was not.

The effect was to ensure that the model was not empirical, and that the claim that lockdowns had saved three million lives was simply an assertion, not a conclusion based on evidence. In December last year, Nature published an article pointing out this and other fundamenta­l problems with the original paper and its “lockdowns saved three million lives” claim. But by then the claim that lockdowns save millions of lives was firmly establishe­d as “backed by science”.

There are other articles in scientific journals that have made an attempt to quantify the number of lives saved by the imposition of the package of measures that together comprise “lockdown”. But they all suffer from essentiall­y the same problem: they start by assuming that lockdowns cause the fall in deaths and infections. They then build that assumption into the model that they use to calculate what would have happened had the lockdowns not been imposed — rather than first providing evidence which establishe­s the truth of that connection, and only

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using it to calculate the number of lives that have been saved by the imposition of lockdown measures.

There is another way of testing whether lockdowns cause a substantia­l fall in infection and death rates. It is to compare the infection and death rates in countries which have imposed lockdowns with the rates in those which have not. Studies have been published in the Lancet and Frontiers in Public

Health which do precisely that.

But their results do not confirm that lockdowns cause a lowering of the infection and death rate from Covid-19. On the contrary: the authors of both those papers report that they find “no associatio­n” between lockdowns and lowered infection and death rates. It’s not that the evidence they collected fails to establish that lockdowns cause a fall in infection and death rates. The evidence doesn’t even support a statistica­l correlatio­n between the imposition of lockdowns and a fall in infection and death rates.

These studies do not claim that infection and death rates never fall after countries impose lockdowns. They obviously have done so, in Australia and New Zealand, for instance. Rather, these studies demonstrat­e that the data collected so far do not show that a fall in infection and death rates is correlated with the imposition of a lockdown.

Even if the data did show that associatio­n, it would not be enough to show lockdowns cause infection and death rates to fall. That one event happens after another event does not show that the first event caused the second. To assume it must do so is to make the same mistake as the man who found he woke up with a headache every morning after he drank gin and tonic — so he stopped drinking tonic. The history of medicine is full of cases where a causal relationsh­ip has been claimed on the basis that two events were correlated — but on closer investigat­ion, the events turned out not to be related as cause and effect.

Critics have pointed out that there are so many difference­s in the way the population­s of different countries react to the disease, and in the measures that their government­s use to fight it, and even in the ways they measure it, that cross-country comparison­s have little value in establishi­ng anything reliable about whether lockdowns do or do not work to reduce infections. That is why a study which compares different provinces within a single country would be more helpful in the quest to establish whether or not lockdowns cause infection and death rates to fall in the countries that impose them. And one which does precisely that has recently been published.

Kasper Planeta Kepp and Christian Bjørnskov

looked at North Jutland, a single province of Denmark which is remarkably homogeneou­s: its population has essentiall­y the same age and health profile, the same culture and a broadly similar level of prosperity. This means that many of the problems that make it difficult to draw reliable conclusion­s from studies that compared two or more different countries do not apply.

North Jutland is divided into 11 municipali­ties. It is a centre for Denmark’s mink farms. Last November, when there was a concern that a new strain of Covid could jump from mink to people, seven of those 11 municipali­ties imposed a lockdown: they issued stay-at-home orders, and closed non-essential busithen

nesses, schools and colleges. The other four municipal areas did not impose any of those measures.

Kepp and Bjørnskov compared what happened to Covid infection and death rates in the municipali­ties which imposed a lockdown with what happened in those that did not. They found that the reduction in infection and death rates followed an almost identical pattern in both.

It is very striking evidence that lockdowns are not effective in reducing infection and death rates, but it does not appear to have persuaded many of the scientists who study Covid. In particular, Sir Patrick Vallance and Professor Whitty continue to insist that, prior to inoculatin­g 70 per cent of the population, lockdowns are the only effective way of combating Covid.

They may think that studies are not needed to establish so elementary a point as the effectiven­ess of lockdowns in controllin­g infectious viruses that spread in droplets in the air travelling from person to person. It is a fundamenta­l principle governing infectious diseases spread by human contact that if you do not have contact with another individual, you cannot infect, or be infected by, them. And in this the Chief Scientific Officer and the Chief Medical Officer are surely right: it is a fundamenta­l principle. So lockdowns must work after all, right?

Wrong. It doesn’t follow that lockdowns must work to diminish infections and deaths from Covid. The problem is not with the principle but with putting it into practice. If no one meets with anyone else, that will indeed completely prevent the spread of new infections — but a lockdown will only have that effect if there is perfect compliance. But complete isolation for everyone is obviously not a feasible option. No society can function when literally everyone goes into rigorous self-isolation. The laws governing lockdowns rightly recognise that there have to be exceptions to the rules because many thousands of people work in vital services and industries — such as the provision of food and medical care, the maintenanc­e of law and order, maintainin­g the electricit­y, water and gas networks, and so on — who have to be able to continue to interact with others if our society is not to collapse.

Let us assume that lockdowns

could in theory be effective in reducing Covid infection and death rates even when exceptions are made for a minimum of 15 per cent of the population. What would be the problem? Again, the problem isn’t with the theory. It’s with practice. There are clearly profound practical difficulti­es in getting a high level of compliance from the other 85 per cent of the population. Many people are reluctant only to leave home when they have a reason for going out that is accepted by the government. The government is aware of this. That is why it is running the advertisin­g campaign stating Bending the rules costs lives.

What degree of compliance is needed from the 85 per cent of the population that don’t do essential jobs in order for lockdowns to be effective? I don’t think that anyone knows the answer to that question. But there is plenty of evidence to suggest that, whatever the needed degree of compliance is, we in the UK have not reached it. Could we achieve the necessary level of compliance, whatever that level of compliance turns out to be?

Again, in theory, we could — but the problem is once again with practice. Any government can in theory achieve 100 per cent compliance with any policy if it imposes sufficient­ly draconian punishment­s, backed up by a sufficient­ly high chance of enforcemen­t. The government could impose the death penalty for breaking lockdown rules. I take it that no one in their right mind would want to go that far, though it might be very effective in cutting infection rates.

But the government could easily impose much stricter punishment­s for people who do not comply with lockdown rules. Should it? My strong conviction is that it should not, even if it turns out to be true that strictly enforced lockdowns significan­tly reduce the spread of Covid-19. China and North Korea are societies where the police have the kind of powers necessary to enforce uniform compliance with lockdown rules. I do not want to live in that kind of society. I hope that most other British citizens view that outcome with the same alarm that I do.

Acommon response to suggesting that lockdowns are not worth their costs is to say that the only alternativ­e to a lockdown is letting Covid-19 rip through our society unchecked — and that, the critics say, would lead to far higher death rates and a totally overwhelme­d NHS. But the dichotomy is a false one. It is not true that the only options are either having a full lockdown or doing nothing at all to try to diminish Covid infection and death rates. Ending the lockdown does not mean

The problem with lockdowns is not the principle, but putting it into practice. It will only be effective if there is perfect compliance

 ??  ?? Emotive language: Covid-19 messaging at Piccadilly Circus
Emotive language: Covid-19 messaging at Piccadilly Circus
 ??  ?? “40 quid — result! Just goes to show, sometimes good things come from bad,” said the boy.
“40 quid — result! Just goes to show, sometimes good things come from bad,” said the boy.

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