The Daily Telegraph

Statins found to make heart healthier and more effective

- By Sarah Knapton SCIENCE EDITOR

STATINS not only lower cholestero­l but also repair the heart and restore lost function, a new study suggests.

Around six million people in Britain are prescribed statins but many do not take them over fears of debilitati­ng side-effects.

New research by Queen Mary University of London shows they not only lower cholestero­l but also appear to improve heart health.

The team used magnetic resonance scanning (MRI) to look into the hearts of 4,622 men and women in their 60s from the UK Biobank, of whom 785 were taking statins.

Compared with untreated individual­s, patients prescribed statins had lower left ventricula­r heart chambers containing 2.4 per cent less muscle mass, meaning their hearts were fitter. healthier and more able to pump blood effectivel­y.

The effect was striking because those prescribed statins had been judged to have the biggest risk of heart problems, had higher BMIS, higher blood pressure and were on average four years older.

“People using statins were less likely to have a thickened heart muscle and less likely to have a large heart chamber,” said lead scientist Dr Nay Aung.

“Having a thick, large heart is a strong predictor of future heart attack, heart failure or stroke, and taking statins appears to reverse the negative changes in the heart.”

The findings were presented at EUROCMR 2017, a conference on heart imaging taking place in Prague, Czech Republic.

Since 2014 the majority of men aged over 60 and women over 65 have been offered statins, even if they only have a one in 10 chance of developing cardiovasc­ular disease within 10 years.

However, some doctors believe it is wrong to medicate people who are generally healthy and some studies have suggested statins have side effects including muscle pain and diminished cognitive function.

Heart charities claim there is growing evidence that statins are beneficial beyond simply lowering cholestero­l.

Previous studies have found that the drugs also improve blood vessel function and reduce inflammati­on.

Prof Jeremy Pearson, associate medical director at the British Heart Foundation, said: “This study is one of many which suggest statins have other effects on our heart health, though few have been proven.

“By using the power of the largescale imaging studies from the UK Biobank, this study indicates that statins may have a direct effect on the heart’s structure that we haven’t been able to detect until now.”

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