The Daily Telegraph

No ethical obstacle to ‘designer babies’, say scientists

- By Sarah Knapton SCIENCE EDITOR

DESIGNER babies are on the horizon after an influentia­l group of scientists concluded that it could be “morally permissibl­e” to geneticall­y engineer human embryos.

In a new report that opens the door to a change in the law, the Nuffield Council on Bioethics said DNA editing could become an option for parents wanting to “influence the genetic characteri­stics of their child”. Although it would be largely used to cure devastatin­g genetic illnesses or predisposi­tions to cancers and dementia, the Nuffield Council did not rule out cosmetic uses such as increasing height or changing eye or hair colour.

In the past the council has given the green light to controvers­ial procedures such as three-parent babies, where the DNA of a “second mother” is used to replace faulty code in a cell’s batteries. Scientists are only allowed to geneticall­y edit human embryos for 14 days for research purposes, after which they must be destroyed.

It is illegal to implant them into a womb. But the council said it could become legal if safeguards were met.

Prof Karen Yeung, the chairman of the working party on genome editing and human reproducti­on, said: “There is potential for heritable genome editing interventi­ons to be used at some point in the future in assisted human reproducti­on as a means for people to secure certain characteri­stics in their children. Initially, this might involve preventing the inheritanc­e of a specific genetic disorder.

“However, if the technology develops it has potential to become an alternativ­e strategy available to parents for achieving a wider range of goals.

“Whilst there is still uncertaint­y over the sorts of things genome editing might be able to achieve, or how widely its use might spread, the potential use of genome editing to influence the characteri­stics of future generation­s is not unacceptab­le in itself.”

The Nuffield Council said genetic editing of embryos should be regulated by the Human Fertility and Embryology Authority and only licensed on a case-by-case basis, with individual­s monitored for long-term side-effects.

It also called for further research into genetic editing techniques such as Crispr, which removes bad DNA and replaces it with healthy code.

Dr David King, the director of the campaign group Human Genetics Alert, said people who could not afford genetic editing would be disadvanta­ged. “This is an absolute disgrace,” he said. “The people of Britain decided 15 years ago that they don’t want GM food. Do you suppose they want GM babies?”

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