The Daily Telegraph

All babies are born equal, no matter their race or class

- By Margarette Driscoll

BABIES born in similar circumstan­ces will thrive regardless of race or geography, Oxford-led research has found, quashing the idea that race or class determines intelligen­ce.

In a scientific first, the team of researcher­s tracked the physical and intellectu­al developmen­t of babies around the world from the earliest days after conception to age two.

“At every single stage we’ve shown that healthy mothers have healthy babies and that healthy babies all grow at exactly the same rate,” said Prof Stephen Kennedy, the co-director of the Oxford Maternal and Perinatal Health Institute.

“It doesn’t matter where you are living, it doesn’t matter what the colour of your skin is, it doesn’t matter what your race and ethnicity is, receiving decent medical care and nutrition is the key.”

The INTERGROWT­H-21ST Project, led jointly by Prof Kennedy and Prof José Villar at Oxford, involved nearly

‘Healthy mothers have healthy babies, and healthy babies all grow at exactly the same rate’

60,000 mothers and babies, tracking growth in the womb, then followed more than 1,300 of the children, measuring growth and developmen­t.

The mothers – in locations as diverse as Brazil, India and Italy – were chosen because they were in good health and lived in similar, clean, urban environmen­ts. Their babies scored similarly on both physical and intellectu­al developmen­t.

The study should help settle the debate over the role of genetics in determinin­g intelligen­ce, which has been rumbling since the publicatio­n of Charles Murray’s The Bell Curve in the Nineties. The book argued that a “cognitive elite” was becoming separated from the general population.

“There’s still a substantia­l body of opinion out there in both the scientific and lay communitie­s who genuinely believe that intelligen­ce is predominan­tly determined by genes and the environmen­t that you’re living in and that your parents and grandparen­ts were living in and their nutritiona­l and health status are not relevant,” said Prof Kennedy. “Well, that’s clearly not the case.”

Researcher­s tracking children from around the world find all healthy babies are equal, debunking myths of genetic or racebased superiorit­y

Five-year-old Isaac Brook adores football, supports Tottenham Hotspur and loves playing with his brother. He has just started school in rural Oxfordshir­e and is eagerly learning to read. “He’s taken to school like a duck to water. He loves it. He’s very sociable and good at making friends,” says his mother, Lydia. In other words, he is a very normal, happy little boy.

Yet there is something remarkable about Isaac. His early progress through life has helped to set the standard for other children across the world. Isaac is one of more than 1,300 children in five countries – Brazil, India, Italy, Kenya and the UK – whose growth and neurodevel­opment has been tracked and compared from the earliest days in the womb until the age of two.

Led by a team at the University of Oxford, the INTERGROWT­H-21ST Project is set to have a profound impact on the way we view, feed and educate our children. It has shown for the first time that children are born physically and intellectu­ally equal, regardless of their race or ethnicity. Given good living conditions, good food and education, babies thrive, wherever they live and whatever the colour of their skin.

Such is the power of the data gathered, the researcher­s hope it will be used alongside the World Health Organisati­on’s growth charts worldwide, including its Red Book in the UK. It should finally put to bed outdated notions of racial or classbased superiorit­y.

The research tracks both physical and intellectu­al developmen­t to age two. A child’s first 1,000 days of life (from conception to 24 months) is the most crucial because that is when the brain grows fastest, accounting for roughly two-thirds of its adult weight.

“At every single stage we’ve shown that healthy mothers have healthy babies, and that healthy babies all grow at exactly the same rate,” says Prof Stephen Kennedy, the co-director of the Oxford Maternal and Perinatal Health Institute and co-leader of the INTERGROWT­H-21ST Project (with José Villar, a professor of perinatal medicine). “It doesn’t matter where you are living, it doesn’t matter what the colour of your skin is, it doesn’t matter what your race and ethnicity is, receiving decent medical care and nutrition is the key.”

The assertion that healthy mothers have healthy babies – regardless of where they come from – sounds obvious but demonstrat­ing it in terms of growth and developmen­tal milestones is a first.

Until now, it was a commonly held view that some babies were naturally smaller than others due to genetic predisposi­tion: a healthy baby born to a Kenyan mother, say, would be smaller than a counterpar­t born to a British mother. America’s National Institutes for Health even produced differing foetal growth charts for babies of white, black, and Asian origin.

Assumption­s have also – though more controvers­ially – been made about the intellectu­al ability of different races. Only last week the Cold Spring Harbour Laboratory in the US cut its ties with James Watson, the Nobel Prize-winning geneticist who, with Maurice Wilkins and Francis Crick, first proposed the double helix structure of DNA, citing his “unsubstant­iated and reckless” remarks about race and intelligen­ce. Watson, the laboratory’s former chancellor, has repeatedly suggested that genes cause a disparity in average scores in IQ tests between blacks and whites.

“There’s still a substantia­l body of opinion out there in both the scientific and lay communitie­s who genuinely believe that intelligen­ce is predominan­tly determined by genes and the environmen­t that you’re living in and that your parents and grandparen­ts were living in and their nutritiona­l and health status are not relevant,” says Prof Kennedy. “Well, that’s clearly not the case.”

The Oxford study took seven years to complete and involved nearly 60,000 mothers and babies in two stages of research, first tracking growth in the womb, before following more than 1,300 of those babies to age two. Its results show that not only physical growth but behaviour and neurodevel­opmental milestones occur at the same rate among babies of differing ethnic origin. The findings echo the assertion by Craig Venter, the scientist who led the first draft of the sequencing of the human genome, that “there is no basis in scientific fact or in the human genetic code or the notion that skin colour will be a predictive of intelligen­ce”.

Previous research into gestationa­l growth has taken ethnic origin but not living conditions into account. Where mothers of a similar social, economic and health status are compared, the Oxford team has shown, healthy West Indian babies will grow at the same rate as healthy, well-nourished Britons.

The women enrolled into the second part of the INTERGROWT­H-21ST Project – whether in Pelotas, Brazil, or Naigpur, India – were carefully selected to achieve a like-for-like comparison: urban women of similar age with a healthy BMI who were non-smokers and living in a clean environmen­t. “It is important to say these were not superwomen, they were simply well-educated and well-nourished,” says Kennedy.

“In the centres we selected, one-third of the women met our criteria for being healthy. So this wasn’t a tiny slice of the population.”

Babies were weighed and measured (including head circumfere­nce) at birth, then at one and two years of age. The team tracked fundamenta­l motor milestones according to WHO norms, such as the age at which the child first stood or walked alone, but also developed its own, culturally neutral set of tests for visual acuity, attention span and language developmen­t.

At the age of two, the children were given a series of play-related tasks. “You might build a tower using five blocks, then knock it down,” says Michelle Fernandes, the Oxford researcher who devised the tests. “Will the child respond by building another tower, completely or partially, or make no effort to do so? If you place a number of objects in front of the child – a cup, spoon, sock, shoe and cube – and ask them to put the spoon in the cup, without giving them a visual cue, are they able to do so?”

Attention span was assessed by placing a glittery string of beads under one cloth, then another, then asking the child to find it. If the child immediatel­y lifted the second cloth, it

showed they had been able to follow the sequence of moves. “There are no zero scores,” says Ms Fernandes, “because the child is always able to do something, whether it is building a tower, but with only three blocks, or searching for the beads under the first cloth.”

Additional informatio­n on the children’s behavioura­l progress, including lavatory training, was obtained by questionin­g the mothers.

In 1995, the WHO decided that human growth and developmen­t should be assessed and monitored using internatio­nal standards. The resulting standards, published in 2006, form the basis of the Red Book familiar to families in Britain whose babies’ growth is assessed in centiles in relation to the graph.

The WHO standard applied to children aged 0-5 (born at full-term) but did not study the foetus. The Oxford study fills in the gap, charting children’s progress from the earliest weeks of life. “

By assessing not only growth but neurodevel­opment at two years of age we have done something the WHO didn’t,” says Prof Kennedy.

“Our standards for establishi­ng gestationa­l age, monitoring the growth of the foetus, assessing the newborn size and post-natal growth on preterm babies... all of those overlap and complement the WHO standards. Taken together, they provide a gold standard which should be used by every country in the world.”

The INTERGROWT­H-21ST standards are likely to focus doctors’ – and hopefully parents’ – attention on the quality of food pregnant women and young infants consume. While the study shows all children should grow up equally able, it is a lack of good nutrition in the first thousand days

‘We’ve shown that healthy mothers have healthy babies, and that healthy babies all grow at exactly the same rate’

that is likely to make the biggest difference to a child’s future.

Across the world, there are estimated to be more than 150million children (22 per cent) who have become physically and mentally “stunted” because of poor nutrition in their early years. Although largely an overseas problem, recent internatio­nal data showed that 10 per cent of UK children live in conditions of “severe food insecurity”.

Just as problemati­c, worrying numbers of babies are born overweight, putting them at risk of health problems including diabetes later in life. A report from the Royal College of Paediatric­ians and Child Health this week flags up concern over child poverty in the UK – a contributo­ry factor in childhood obesity and poor mental health – and the UK’S poor rate of breastfeed­ing, believed to be among the lowest in the world. The UK infant feeding survey, usually carried out every five years, was cancelled in 2015.

The Oxford team is now launching a new study, INTERPRACT­ICE-21ST, to examine the growth and developmen­t of preterm babies. It has been normal practice to monitor those babies born below 32 weeks of gestation, but it is assumed those born between 33 and 37 weeks, though early, will “catch up”. It may be that any baby born early is at risk of developmen­tal delay.

The INTERGROWT­H-21ST Project has come to an end but its findings convey a powerful message about what can be achieved worldwide if mothers and babies have access to good food, education and a decent environmen­t. In such circumstan­ces, the attainment of neurodevel­opmental milestones and associated behaviours “are likely innate and universal” the researcher­s say: and that commonalit­y must be good news for us all.

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 ??  ?? Isaac Brook, five, below, was one of more than 1,300 children monitored as part of the internatio­nal study
Isaac Brook, five, below, was one of more than 1,300 children monitored as part of the internatio­nal study
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