The Daily Telegraph

Air pollution linked to baldness for first time

Scientists find air pollution reduces levels of proteins the human body needs and can lead to baldness

- Science correspond­ent By Henry Bodkin

Air pollution may cause baldness, scientists have shown for the first time. A study found that fine particulat­e matter emitted by cars damaged the skin that holds hair follicles in place. A series of laboratory tests on human cells showed levels of the crucial proteins needed for hair to grow and be retained decreased the more they were exposed to pollution particles. Researcher­s said exercising indoors rather than in polluted cities could be a way to reduce hair loss.

AIR pollution may cause baldness, scientists have shown for the first time.

A study found that fine particulat­e matter emitted by cars damaged the skin that holds hair follicles in place.

A series of laboratory tests on human cells showed levels of the crucial proteins needed for hair to grow and be retained decreased the more they were exposed to pollution particles.

While there is a growing body of evidence to show how these tiny particles can damage internal health, including by entering the bloodstrea­m through the lungs, it is the first to demonstrat­e such a risk to the surface of the body.

Researcher­s said exercising indoors rather than in polluted cities could be a way to reduce hair loss.

The study was conducted by exposing human follicle dermal papilla cells (HFDPCS) to various concentrat­ions of Pm10-like – particulat­e 10 micrometer­s or less in diameter – dust and diesel particulat­e. After 24 hours, the researcher­s performed a process, known as western blotting, to detect the levels of specific proteins in the cells.

The results showed the presence of PM10 and diesel particulat­e decreased levels of Beta-catenin, a protein responsibl­e for hair growth.

They also revealed the levels of three other proteins – cyclin D1, cyclin E and CDK2 – responsibl­e for hair growth and hair retention, were decreased by Pm10-like dust and diesel particulat­e in a “dose-dependent” manner.

Dr Hyuk Chul Kwon, who led the study at the Future Science Research Centre, South Korea, said: “While the link between air pollution and serious diseases such as cancer, COPD and CVD are well establishe­d there is little to no research on the effect of particular matter exposure on the human skin and hair in particular. Our research explains the mode of action of air pollutants on human follicle dermal papilla cells, showing how the most common air pollutants lead to hair loss.”

Recent research in China, found men in their 20s were going bald sooner than previous generation­s. Although balding is typically associated with ageing, an increasing number of millennial­s in the US say they are experienci­ng hair loss.

Two thirds of all men will eventually be affected. This means roughly 7.4million UK men are losing their hair.

Genetic factors remain the most influentia­l known cause of baldness.

Particulat­e matter sources include burning fossil fuels – including petrol, diesel and solid-fuels such as coal, oil and biomass – as well as industrial activities such as building, mining and manufactur­ing building materials such as cement, ceramics and bricks.

“While it is difficult to escape ambient pollution, limiting time walking on busy streets, especially during rush hour, should help to reduce exposure,” said Mr Kwon. “If you are exercising outdoors, try to do so in areas that are less polluted and do not spend too much time waiting at traffic hotspots such as traffic lights.”

The study is being presented at the European Academy of Dermatolog­y and Venereolog­y Congress, Madrid.

Earlier this year, a study published in the European Heart Journal showed that pollution is now killing nearly as many people as smoking in Britain.

The data suggested the toll is approachin­g 64,000 a year, compared to 78,000 deaths caused by tobacco.

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