The Daily Telegraph

Scientists warn that using mouthwash may damage dental health

- By Georgina Hayes

WHILE many Britons use mouthwash each day to improve their dental hygiene, a new study has found it could damage their teeth.

Researcher­s at the University of Plymouth have found a commonly used type of mouthwash could make saliva significan­tly more acidic.

The study, the first of its kind, examined the effect of chlorhexid­ine mouthwash on the oral microbiome.

It concluded that using the mouthwash significan­tly increases the abundance of lactate-producing bacteria that lower the ph of the saliva.

The work, published in Scientific Reports, involved 36 participan­ts being given placebo mouthwash for seven days, followed by seven days of a chlorhexid­ine mouthwash.

Researcher­s carried out analysis of bacteria in the mouth, as well as measuring ph, saliva buffering capacity (which is the ability to neutralise acids in the mouth), lactate, glucose, nitrate and nitrite concentrat­ions.

They found using chlorhexid­ine led to a greater abundance of species within the Firmicutes and Proteobact­eria bacteria families, and fewer Bacteroide­tes, TM7 and Fusobacter­ia.

This change was associated with an increase in acidity, and chlorhexid­ine was found to reduce microbial diversity in the mouth.

The researcher­s say more work is needed to determine if the reduction in diversity increases the risk of oral disease. Dr Raul Bescos, who led the study, said: “There is a surprising lack of knowledge and literature behind the use of these products.

“Chlorhexid­ine is widely used but research has been limited to its effect on a small number of bacteria linked to particular oral diseases, and most has been carried out in vitro. We believe this is the first study to look at the impact of 7-day use on the whole oral microbiome in human subjects.”

Dr Zoe Brookes, of the University of Plymouth’s Peninsula Dental School, said: “As dental clinicians, we need more informatio­n on how mouthwashe­s alter the balance of oral bacteria, so we can prescribe them correctly.

“This study is an important first step in achieving this.”

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