The Daily Telegraph

The gene that helps block labour pain

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It is estimated that one in 100 women carry the genetic variant KCNG4. Scientists call it a “natural epidural” as it makes it less likely that pain signals will reach the brain during contractio­ns. When pain receptors are stimulated in the uterus during childbirth, they release neurotrans­mitters that send a pain signal to the brain. The KCNG4 gene makes it harder for this process to “switch on”. Therefore, women with the gene should theoretica­lly have a higher pain threshold.

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